PURPOSE: To describe a novel finding of solid-appearing retinal cysts in patients with diabetic macular edema. METHODS: Case series of four patients with diabetic retinopathy discovered to have solid-appearing retinal cysts on spectral-domain optical coherence tomography. RESULTS: These cases demonstrate the presence of inner retinal hyporeflective cysts filled with an isoreflective substance on spectral-domain optical coherence tomography. These solid-appearing cysts arise from previously fluid-filled cysts and are not found in relation to intraretinal hemorrhage. Treatment with intravitreal anti-vascular endothelial growth factor agents did not seem to directly alter their natural course. CONCLUSION: The authors report solid-appearing retinal cysts as a new optical coherence tomography finding in four patients with diabetic macular edema. The exact composition of this isoreflective material is unknown. The authors hypothesize that fibrin or other inflammatory by-products fill these spaces.
PURPOSE: To describe a novel finding of solid-appearing retinal cysts in patients with diabetic macular edema. METHODS: Case series of four patients with diabetic retinopathy discovered to have solid-appearing retinal cysts on spectral-domain optical coherence tomography. RESULTS: These cases demonstrate the presence of inner retinal hyporeflective cysts filled with an isoreflective substance on spectral-domain optical coherence tomography. These solid-appearing cysts arise from previously fluid-filled cysts and are not found in relation to intraretinal hemorrhage. Treatment with intravitreal anti-vascular endothelial growth factor agents did not seem to directly alter their natural course. CONCLUSION: The authors report solid-appearing retinal cysts as a new optical coherence tomography finding in four patients with diabetic macular edema. The exact composition of this isoreflective material is unknown. The authors hypothesize that fibrin or other inflammatory by-products fill these spaces.
Authors: Roberta Farci; Alexandre Sellam; Florence Coscas; Gabriel J Coscas; Giacomo Diaz; Pietro Emanuele Napoli; Eric Souied; Maria Silvana Galantuomo; Maurizio Fossarello Journal: Biomed Res Int Date: 2019-03-20 Impact factor: 3.411
Authors: Marion R Munk; Gabor Mark Somfai; Marc D de Smet; Guy Donati; Marcel N Menke; Justus G Garweg; Lala Ceklic Journal: Int J Mol Sci Date: 2022-07-08 Impact factor: 6.208
Authors: Amir H Kashani; Kyle M Green; Julie Kwon; Zhongdi Chu; Qinqin Zhang; Ruikang K Wang; Sean Garrity; David Sarraf; Carl B Rebhun; Nadia K Waheed; Karen B Schaal; Marion R Munk; Sarra Gattoussi; K Bailey Freund; Fang Zheng; Guanghui Liu; Philip J Rosenfeld Journal: Ophthalmol Retina Date: 2017-12-15