Rohan J Shah1, Netan Choudhry, Yannek I Leiderman. 1. *Department of Ophthalmology and Visual Sciences, Eye and Ear Infirmary, University of Illinois at Chicago, Chicago, Illinois †Herzig Eye Institute, Toronto, Ontario, Canada.
Abstract
PURPOSE: To report a case of Purtscher-like retinopathy in association with capecitabine chemotherapy for metastatic pancreatic adenocarcinoma. METHODS: Case report. RESULTS: Bilateral retinal hemorrhages and cotton-wool spots in a predominantly juxtapapillary distribution were observed coincident with decreased vision. There was gradual improvement of the retinopathy and patient's vision over several months until the time of death. CONCLUSION: Metastatic pancreatic cancer and capecitabine, a fluoropyrimidine chemotherapeutic agent, are a rare cause of Purtscher-like retinopathy.
PURPOSE: To report a case of Purtscher-like retinopathy in association with capecitabine chemotherapy for metastatic pancreatic adenocarcinoma. METHODS: Case report. RESULTS:Bilateral retinal hemorrhages and cotton-wool spots in a predominantly juxtapapillary distribution were observed coincident with decreased vision. There was gradual improvement of the retinopathy and patient's vision over several months until the time of death. CONCLUSION:Metastatic pancreatic cancer and capecitabine, a fluoropyrimidine chemotherapeutic agent, are a rare cause of Purtscher-like retinopathy.