PURPOSE: To report the first successful medical treatment of ophthalmomyiasis interna posterior without associated surgical treatment. METHOD: Interventional case report. The patient is an 11-year-old boy with panuveitis and neuroretinitis associated with a pathognomonic presentation of ophthalmomyiasis interna posterior in which the larva could not be identified. The patient received medical treatment with a single oral dose of ivermectin of 200 mg/kg followed by systemic steroid therapy without associated surgical extraction of the larva via pars plana vitrectomy or laser photocoagulation. RESULTS: Anterior and posterior uveitis resolution, reversal of neuroretinitis, and visual acuity improvement. CONCLUSION: Medical treatment with ivermectin can be considered as primary therapeutic modality in ophthalmomyiasis interna posterior.
PURPOSE: To report the first successful medical treatment of ophthalmomyiasis interna posterior without associated surgical treatment. METHOD: Interventional case report. The patient is an 11-year-old boy with panuveitis and neuroretinitis associated with a pathognomonic presentation of ophthalmomyiasis interna posterior in which the larva could not be identified. The patient received medical treatment with a single oral dose of ivermectin of 200 mg/kg followed by systemic steroid therapy without associated surgical extraction of the larva via pars plana vitrectomy or laser photocoagulation. RESULTS: Anterior and posterior uveitis resolution, reversal of neuroretinitis, and visual acuity improvement. CONCLUSION: Medical treatment with ivermectin can be considered as primary therapeutic modality in ophthalmomyiasis interna posterior.
Authors: Podjanee Jittamala; Wuelton Monteiro; Menno R Smit; Belen Pedrique; Sabine Specht; Carlos J Chaccour; Céline Dard; Pascal Del Giudice; Virak Khieu; Annabel Maruani; Virgilio E Failoc-Rojas; Marimar Sáez-de-Ocariz; Antoni Soriano-Arandes; Jaime Piquero-Casals; Anne Faisant; Marie-Pierre Brenier-Pinchart; David Wimmersberger; Jean T Coulibaly; Jennifer Keiser; Franck Boralevi; Oliver Sokana; Michael Marks; Daniel Engelman; Lucia Romani; Andrew C Steer; Lorenz von Seidlein; Nicholas J White; Eli Harriss; Kasia Stepniewska; Georgina S Humphreys; Kalynn Kennon; Philippe J Guerin; Kevin C Kobylinski Journal: PLoS Negl Trop Dis Date: 2021-03-17