Beatriz S Takahashi1, Claudia Bruè, Richard F Spaide. 1. From the Vitreous, Retina, Macula Consultants of New York, and the LuEsther T. Mertz Retinal Research Center, Manhattan Eye, Ear, and Throat Hospital, New York, New York.
Abstract
PURPOSE: To report the autofluorescence features of congenital hypertrophy of the retinal pigment epithelium (CHRPE). METHODS: Four patients with CHRPE were evaluated using autofluorescence in a camera-based system. RESULTS: All CHRPE lesions studied had well demarcated borders and were hypoautofluorescent. Presence of a hypopigmented halo and lacunae did not alter the homogeneous hypofluorescence. CONCLUSION: Hypoautofluorescence confirmed the known absence of lipofuscin in the retinal pigment epithelium cells of CHRPE lesions. Autofluorescence imaging may provide useful information in evaluating pigmented lesions of the fundus.
PURPOSE: To report the autofluorescence features of congenital hypertrophy of the retinal pigment epithelium (CHRPE). METHODS: Four patients with CHRPE were evaluated using autofluorescence in a camera-based system. RESULTS: All CHRPE lesions studied had well demarcated borders and were hypoautofluorescent. Presence of a hypopigmented halo and lacunae did not alter the homogeneous hypofluorescence. CONCLUSION: Hypoautofluorescence confirmed the known absence of lipofuscin in the retinal pigment epithelium cells of CHRPE lesions. Autofluorescence imaging may provide useful information in evaluating pigmented lesions of the fundus.