PURPOSE: To report a case of cutaneous melanoma metastatic to the vitreous cavity. METHODS: Retrospective case report. A 72-year-old white man with a history of cutaneous melanoma but no known distant metastases presented with floaters and decreased vision. RESULTS: The patient was initially treated for a presumptive diagnosis of ocular toxoplasmosis. After failure to respond to treatment, he underwent diagnostic pars plana vitrectomy. Pathology of the vitreous specimen was suggestive of metastatic melanoma, and systemic workup revealed metastases to the brain. CONCLUSION: In patients with a known history of cutaneous melanoma presenting with ocular inflammation, a high index of suspicion for metastatic disease should be maintained.
PURPOSE: To report a case of cutaneous melanoma metastatic to the vitreous cavity. METHODS: Retrospective case report. A 72-year-old white man with a history of cutaneous melanoma but no known distant metastases presented with floaters and decreased vision. RESULTS: The patient was initially treated for a presumptive diagnosis of ocular toxoplasmosis. After failure to respond to treatment, he underwent diagnostic pars plana vitrectomy. Pathology of the vitreous specimen was suggestive of metastatic melanoma, and systemic workup revealed metastases to the brain. CONCLUSION: In patients with a known history of cutaneous melanoma presenting with ocular inflammation, a high index of suspicion for metastatic disease should be maintained.
Authors: Lesley Everett; Bertil E Damato; Michele M Bloomer; James D Palmer; Andrew A Kao; Jay M Stewart; Armin R Afshar Journal: Ocul Oncol Pathol Date: 2018-08-08