Shantan Reddy1, Jay Klancnik, Marcus S Edelstein, Brian Marr, Michael J Cooney. 1. From the *Department of Ophthalmology, Manhattan Eye, Ear & Throat Hospital and New York University School of Medicine, New York, New York; †Vitreous-Retina-Macula Consultants of New York, New York, New York; ‡State University of New York Downstate Medical Center, Brooklyn, New York; and §Wills Eye Hospital, Philadelphia, Pennsylvania.
Abstract
PURPOSE: To describe a fundus autofluorescent photographic pattern in a case of bilateral diffuse uveal melanocytic proliferation (BDUMP) with occult esophageal carcinoma. METHODS: Observational case report. RESULTS: Color photography captured multiple round areas of discoloration throughout the fundus in a background of orange pigmentation that may have represented a lipofuscin-laden retinal pigment epithelium (RPE). Autofluorescence photography showed extensive nummular areas of hypoautofluorescence interspersed between areas of hyperautofluorescence as a result of extensive deposition of lipofuscin within the RPE. CONCLUSION: Our case attests to the utility of autofluorescence photography as a sensitive, noninvasive imaging modality for the early detection of BDUMP.
PURPOSE: To describe a fundus autofluorescent photographic pattern in a case of bilateral diffuse uveal melanocytic proliferation (BDUMP) with occult esophageal carcinoma. METHODS: Observational case report. RESULTS: Color photography captured multiple round areas of discoloration throughout the fundus in a background of orange pigmentation that may have represented a lipofuscin-laden retinal pigment epithelium (RPE). Autofluorescence photography showed extensive nummular areas of hypoautofluorescence interspersed between areas of hyperautofluorescence as a result of extensive deposition of lipofuscin within the RPE. CONCLUSION: Our case attests to the utility of autofluorescence photography as a sensitive, noninvasive imaging modality for the early detection of BDUMP.