Literature DB >> 25387503

Skin gangrene as an extraintestinal manifestation of inflammatory bowel disease.

Yumi Cristina Komatsu1, Gabriela Cunha Capareli1, Maria Fernanda Feitosa de Camargo Boin1, Rute Lellis1, Thaís Helena Proença de Freitas1, Karine Simone1.   

Abstract

Inflammatory bowel diseases can commonly present many cutaneous lesions which can contribute to the diagnosis of the disease or its activity. The most frequent cutaneous or mucocutaneous manifestations suggesting ulcerative rectocolitis activity are erythema nodosum (3-10%), pyoderma gangrenosum (5-12%) and aphthous stomatitis (4%). Other reactive skin manifestations related to immunological mechanisms associated with the inflammatory bowel disease are: Sweet's syndrome, arthritis-dermatitis syndrome associated with inflammatory bowel disease and leukocytoclastic vasculitis. We describe the case of a young man with diagnosis of ulcerative rectocolitis, which presented an extensive cutaneous gangrene secondary to microvascular thrombosis. The case represents a dermatologic rarity and should be recognized as a cutaneous manifestation related to the hypercoagulability state observed in the disease's activity.

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Year:  2014        PMID: 25387503      PMCID: PMC4230667          DOI: 10.1590/abd1806-4841.20143001

Source DB:  PubMed          Journal:  An Bras Dermatol        ISSN: 0365-0596            Impact factor:   1.896


  5 in total

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Journal:  N Engl J Med       Date:  1995-04-06       Impact factor: 91.245

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Journal:  Clin Exp Dermatol       Date:  1989-09       Impact factor: 3.470

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Authors:  S Singh; K Noshirwani
Journal:  Postgrad Med J       Date:  1996-10       Impact factor: 2.401

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Authors:  M J Webberley; M T Hart; V Melikian
Journal:  Gut       Date:  1993-02       Impact factor: 23.059

5.  Skin manifestations of inflammatory bowel disease.

Authors:  Brian L Huang; Stephanie Chandra; David Quan Shih
Journal:  Front Physiol       Date:  2012-02-06       Impact factor: 4.566

  5 in total
  2 in total

1.  Cutaneous thrombotic vasculopathy related to poorly controlled ulcerative colitis.

Authors:  Justin Cheeley; Brenda Morales-Pico; Suzana John
Journal:  JAAD Case Rep       Date:  2018-08-09

2.  Thrombotic cutaneous gangrene associated with ulcerative colitis.

Authors:  Justine Galambus; Leigh Ann Hatch; Nupur Patel; Alejandro Rabionet; Wei-Shen Chen; Lilia Correa-Selm
Journal:  JAAD Case Rep       Date:  2022-08-10
  2 in total

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