Literature DB >> 25387117

Genetically engineered livestock: ethical use for food and medical models.

Lydia C Garas1, James D Murray, Elizabeth A Maga.   

Abstract

Recent advances in the production of genetically engineered (GE) livestock have resulted in a variety of new transgenic animals with desirable production and composition changes. GE animals have been generated to improve growth efficiency, food composition, and disease resistance in domesticated livestock species. GE animals are also used to produce pharmaceuticals and as medical models for human diseases. The potential use of these food animals for human consumption has prompted an intense debate about food safety and animal welfare concerns with the GE approach. Additionally, public perception and ethical concerns about their use have caused delays in establishing a clear and efficient regulatory approval process. Ethically, there are far-reaching implications of not using genetically engineered livestock, at a detriment to both producers and consumers, as use of this technology can improve both human and animal health and welfare.

Entities:  

Keywords:  agricultural sustainability; animal welfare; food production; transgenic

Mesh:

Year:  2014        PMID: 25387117     DOI: 10.1146/annurev-animal-022114-110739

Source DB:  PubMed          Journal:  Annu Rev Anim Biosci        ISSN: 2165-8102            Impact factor:   8.923


  6 in total

1.  The growth and reproduction performance of TALEN-mediated β-lactoglobulin-knockout bucks.

Authors:  Hengtao Ge; Chenchen Cui; Jun Liu; Yan Luo; Fusheng Quan; Yaping Jin; Yong Zhang
Journal:  Transgenic Res       Date:  2016-06-07       Impact factor: 2.788

2.  Expression of Active Fluorophore Proteins in the Milk of Transgenic Pigs Bypassing the Secretory Pathway.

Authors:  Ayan Mukherjee; Wiebke Garrels; Thirumala R Talluri; Daniela Tiedemann; Zsuzsanna Bősze; Zoltán Ivics; Wilfried A Kues
Journal:  Sci Rep       Date:  2016-04-18       Impact factor: 4.379

3.  One-step Multiplex Transgenesis via Sleeping Beauty Transposition in Cattle.

Authors:  Wiebke Garrels; Thirumala R Talluri; Ronja Apfelbaum; Yanet P Carratalá; Pablo Bosch; Kerstin Pötzsch; Esther Grueso; Zoltán Ivics; Wilfried A Kues
Journal:  Sci Rep       Date:  2016-02-24       Impact factor: 4.379

Review 4.  Creating Disease Resistant Chickens: A Viable Solution to Avian Influenza?

Authors:  Fong Yang Looi; Michelle L Baker; Thomas Townson; Mathilde Richard; Ben Novak; Tim J Doran; Kirsty R Short
Journal:  Viruses       Date:  2018-10-15       Impact factor: 5.048

Review 5.  Genome Editing of Pigs for Agriculture and Biomedicine.

Authors:  Huaqiang Yang; Zhenfang Wu
Journal:  Front Genet       Date:  2018-09-04       Impact factor: 4.599

6.  Trio-Based Deep Sequencing Reveals a Low Incidence of Off-Target Mutations in the Offspring of Genetically Edited Goats.

Authors:  Chao Li; Shiwei Zhou; Yan Li; Guanwei Li; Yige Ding; Lan Li; Jing Liu; Lei Qu; Tad Sonstegard; Xingxu Huang; Yu Jiang; Yulin Chen; Bjoern Petersen; Xiaolong Wang
Journal:  Front Genet       Date:  2018-10-04       Impact factor: 4.599

  6 in total

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