Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The structure of the flavoenzyme glutathione reductase.

Literature DB >> 25387

The structure of the flavoenzyme glutathione reductase.

G E Schulz, R H Schirmer, W Sachsenheimer, E F Pai.

Abstract

The three-dimensional structure of the dimeric flavoenzyme glutathione reductase from human erythrocytes has been elucidated by an X-ray diffraction analysis at 0.3 nm resolution. The polypeptide chain has been traced, and the binding positions of FAD, NADP and glutathione have been determined. A mechanism for the electron transfer is discussed.

Entities: Chemical Species

Mesh：

Substances：

Year: 1978 PMID： 25387 DOI： 10.1038/273120a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

Keyword Cloud
Cited

33 in total

1. Molecular anatomy: phyletic relationships derived from three-dimensional structures of proteins.

Authors: M S Johnson; M J Sutcliffe; T L Blundell
Journal: J Mol Evol Date: 1990-01 Impact factor: 2.395

2. Structure of glycolate oxidase from spinach.

Authors: Y Lindqvist; C I Brändén
Journal: Proc Natl Acad Sci U S A Date: 1985-10 Impact factor: 11.205

Review 3. Binding energy, conformational change, and the mechanism of transmembrane solute movements.

Authors: G A Scarborough
Journal: Microbiol Rev Date: 1985-09

4. Profiling patterns of glutathione reductase inhibition by the natural product illudin S and its acylfulvene analogues.

Authors: Xiaodan Liu; Shana J Sturla
Journal: Mol Biosyst Date: 2009-07-08

5. Cloning, expression, crystallization and preliminary X-ray studies of the ferredoxin-NAD(P)+ reductase from the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1.

Authors: Pasqual Liauw; Tomohiro Mashiba; Marta Kopczak; Katrin Wiegand; Norifumi Muraki; Hisako Kubota; Yusuke Kawano; Masahiko Ikeuchi; Toshiharu Hase; Matthias Rögner; Genji Kurisu
Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun Date: 2012-08-30

6. The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli.

Authors: L D Arscott; S Gromer; R H Schirmer; K Becker; C H Williams
Journal: Proc Natl Acad Sci U S A Date: 1997-04-15 Impact factor: 11.205

The structure of the flavoenzyme glutathione reductase.

1. Molecular anatomy: phyletic relationships derived from three-dimensional structures of proteins.

2. Structure of glycolate oxidase from spinach.

Review 3. Binding energy, conformational change, and the mechanism of transmembrane solute movements.

4. Profiling patterns of glutathione reductase inhibition by the natural product illudin S and its acylfulvene analogues.

5. Cloning, expression, crystallization and preliminary X-ray studies of the ferredoxin-NAD(P)+ reductase from the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1.

6. The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli.

7. The dual-mode quaternary structure of seminal RNase.

8. Thioredoxin system from Deinococcus radiodurans.

9. Alkyl selenosulphates (seleno Bunte salts). A new class of thiol-blocking reagents.

10. Structures of the multicomponent Rieske non-heme iron toluene 2,3-dioxygenase enzyme system.