OBJECTIVE: The goal of this study was to examine the longitudinal trajectories of posttraumatic stress disorder (PTSD) symptoms in a sample of acutely injured hospitalized civilian trauma survivors who participated in a randomized clinical trial. Prior longitudinal descriptive research has shown that there are distinct trajectories of PTSD symptoms over time in trauma survivors. Limited clinical trial research exists that describes the patterns of the trajectories as well as the risk factors that influence the trajectories for seriously injured trauma-exposed patients. METHOD: Semiparametric, group-based approach trajectory modeling was used to examine four group trajectories of a subset of data obtained from a previous longitudinal clinical trial. Trajectories examined included resilience, recovery, relapsing/remitting, and chronic symptom patterns. One hundred and ninety-four patients who participated in the randomized clinical trial were assessed at baseline in the days and weeks after injury and then randomized. The associations between previously identified PTSD risk factors and the four trajectories were examined. RESULTS: The risk factors of ethnocultural minority status, psychiatric history, additional life stressors, and depressive symptoms, as well as intervention versus control group status, were found to significantly affect the probability of trajectory group membership for PTSD symptom severity. CONCLUSIONS: These findings suggest that there is a need for early PTSD interventions that anticipate differences in injured patients' PTSD trajectory profiles. Stepped care intervention procedures may optimally address the diverse PTSD trajectory patterns observed in injured trauma survivors through the tailoring of intervention timing and dosing.
RCT Entities:
OBJECTIVE: The goal of this study was to examine the longitudinal trajectories of posttraumatic stress disorder (PTSD) symptoms in a sample of acutely injured hospitalized civilian trauma survivors who participated in a randomized clinical trial. Prior longitudinal descriptive research has shown that there are distinct trajectories of PTSD symptoms over time in trauma survivors. Limited clinical trial research exists that describes the patterns of the trajectories as well as the risk factors that influence the trajectories for seriously injured trauma-exposed patients. METHOD: Semiparametric, group-based approach trajectory modeling was used to examine four group trajectories of a subset of data obtained from a previous longitudinal clinical trial. Trajectories examined included resilience, recovery, relapsing/remitting, and chronic symptom patterns. One hundred and ninety-four patients who participated in the randomized clinical trial were assessed at baseline in the days and weeks after injury and then randomized. The associations between previously identified PTSD risk factors and the four trajectories were examined. RESULTS: The risk factors of ethnocultural minority status, psychiatric history, additional life stressors, and depressive symptoms, as well as intervention versus control group status, were found to significantly affect the probability of trajectory group membership for PTSD symptom severity. CONCLUSIONS: These findings suggest that there is a need for early PTSD interventions that anticipate differences in injured patients' PTSD trajectory profiles. Stepped care intervention procedures may optimally address the diverse PTSD trajectory patterns observed in injured trauma survivors through the tailoring of intervention timing and dosing.
Authors: Neil P Roberts; Neil J Kitchiner; Justin Kenardy; Lindsay Robertson; Catrin Lewis; Jonathan I Bisson Journal: Cochrane Database Syst Rev Date: 2019-08-08
Authors: Douglas Zatzick; Stephen S O'Connor; Joan Russo; Jin Wang; Nigel Bush; Jeff Love; Roselyn Peterson; Leah Ingraham; Doyanne Darnell; Lauren Whiteside; Erik Van Eaton Journal: J Trauma Stress Date: 2015-10
Authors: K C Koenen; A Ratanatharathorn; L Ng; K A McLaughlin; E J Bromet; D J Stein; E G Karam; A Meron Ruscio; C Benjet; K Scott; L Atwoli; M Petukhova; C C W Lim; S Aguilar-Gaxiola; A Al-Hamzawi; J Alonso; B Bunting; M Ciutan; G de Girolamo; L Degenhardt; O Gureje; J M Haro; Y Huang; N Kawakami; S Lee; F Navarro-Mateu; B-E Pennell; M Piazza; N Sampson; M Ten Have; Y Torres; M C Viana; D Williams; M Xavier; R C Kessler Journal: Psychol Med Date: 2017-04-07 Impact factor: 7.723
Authors: Jennifer A Sumner; Dennis Rünger; Theodore F Robles; Sarah R Lowe; David Elashoff; Vivek Shetty Journal: J Affect Disord Date: 2021-02-05 Impact factor: 4.839
Authors: Nicholas A Giordano; Therese S Richmond; John T Farrar; Chester C 'Trip' Buckenmaier Iii; Rollin M Gallagher; Rosemary C Polomano Journal: Pain Med Date: 2021-11-26 Impact factor: 3.750