Literature DB >> 25386487

Are we missing hypertrophic cardiomyopathy in pregnancy? Experience of a tertiary care hospital.

Pooja Sikka1, Vanita Suri2, Neelam Aggarwal1, Seema Chopra1, Ajay Bahl3, Rajesh Vijayverghia3.   

Abstract

BACKGROUND: Controversies persist regarding risks associated with pregnancy and delivery in women with hypertrophic cardiomyopathy (HCM). To date, pregnancy outcome data for these patients is scarce. We report the experience of pregnancies with HCM in a tertiary care hospital.
MATERIALS AND METHODS: Data regarding cardiac illness and obstetric profile of all women attending the cardio-obstetrics clinic from January 1990 to December 2012 were studied. The records of cardiac illness of all women were checked and all patients with HCM were included in the study.
RESULTS: Out of total 2016 patients booked in the cardio-obstetrics clinic between 1990 and 2012, only 4 women were found to have a diagnosis of HCM (0.2%). Of these, 2 women with left ventricular outflow tract obstruction and one with non-obstructive HCM had only mild symptoms and tolerated pregnancy and labour well. One patient had HCM with restrictive physiology developed heart failure and intra-uterine fetal death.
CONCLUSION: HCM is underdiagnosed and rarely identified in pregnancy. Most patients with HCM tolerated pregnancy well, howeverone patient with restrictive physiology developed heart failure during her first pregnancy.

Entities:  

Keywords:  Hypertrophic cardiomyopathy; Pregnancy

Year:  2014        PMID: 25386487      PMCID: PMC4225939          DOI: 10.7860/JCDR/2014/9924.4803

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  11 in total

1.  Hyperthrophic obstructive cardiomyopathy and pregnancy: University College London Hospital experience.

Authors:  D Walker; N Kaur; R Bell; F Walker
Journal:  Minerva Anestesiol       Date:  2007-09       Impact factor: 3.051

2.  Pregnancy in patients with heart disease: experience with 1,000 cases.

Authors:  Walkiria Samuel Avila; Eduardo Giusti Rossi; José Antonio Franchini Ramires; Max Grinberg; Maria Rita Lemos Bortolotto; Marcelo Zugaib; Protasio Lemos da Luz
Journal:  Clin Cardiol       Date:  2003-03       Impact factor: 2.882

Review 3.  Systematic review of pregnancy in women with inherited cardiomyopathies.

Authors:  Sébastien P J Krul; Jasper J van der Smagt; Maarten P van den Berg; Krystyna M Sollie; Petronella G Pieper; Karin Y van Spaendonck-Zwarts
Journal:  Eur J Heart Fail       Date:  2011-04-11       Impact factor: 15.534

Review 4.  Current concepts: beta-blockers in pregnancy.

Authors:  P C Rubin
Journal:  N Engl J Med       Date:  1981-11-26       Impact factor: 91.245

5.  ESC Guidelines on the management of cardiovascular diseases during pregnancy: the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC).

Authors:  Vera Regitz-Zagrosek; Carina Blomstrom Lundqvist; Claudio Borghi; Renata Cifkova; Rafael Ferreira; Jean-Michel Foidart; J Simon R Gibbs; Christa Gohlke-Baerwolf; Bulent Gorenek; Bernard Iung; Mike Kirby; Angela H E M Maas; Joao Morais; Petros Nihoyannopoulos; Petronella G Pieper; Patrizia Presbitero; Jolien W Roos-Hesselink; Maria Schaufelberger; Ute Seeland; Lucia Torracca
Journal:  Eur Heart J       Date:  2011-08-26       Impact factor: 29.983

6.  Prevalence of hypertrophic cardiomyopathy in a general population of young adults. Echocardiographic analysis of 4111 subjects in the CARDIA Study. Coronary Artery Risk Development in (Young) Adults.

Authors:  B J Maron; J M Gardin; J M Flack; S S Gidding; T T Kurosaki; D E Bild
Journal:  Circulation       Date:  1995-08-15       Impact factor: 29.690

7.  Prevalence, clinical significance, and genetic basis of hypertrophic cardiomyopathy with restrictive phenotype.

Authors:  Toru Kubo; Juan R Gimeno; Ajay Bahl; Ulla Steffensen; Morten Steffensen; Eyman Osman; Rajesh Thaman; Jens Mogensen; Perry M Elliott; Yoshinori Doi; William J McKenna
Journal:  J Am Coll Cardiol       Date:  2007-06-11       Impact factor: 24.094

8.  Pregnancy related complications in women with hypertrophic cardiomyopathy.

Authors:  R Thaman; A Varnava; M S Hamid; S Firoozi; B Sachdev; M Condon; J R Gimeno; R Murphy; P M Elliott; W J McKenna
Journal:  Heart       Date:  2003-07       Impact factor: 5.994

9.  Influence of pregnancy on clinical course and fetal outcome of women with hypertrophic cardiomyopathy.

Authors:  Walkiria Samuel Avila; Florence M Cavalcanti Amaral; Jose Antonio Franchini Ramires; Eduardo Giusti Rossi; Max Grinberg; Maria Rita Lemos Bortolotto; Charles Mady; José Eduardo Krieger; Marcelo Zugaib
Journal:  Arq Bras Cardiol       Date:  2007-04       Impact factor: 2.000

10.  Risk associated with pregnancy in hypertrophic cardiomyopathy.

Authors:  Camillo Autore; Maria Rosa Conte; Marco Piccininno; Paola Bernabò; Giovanna Bonfiglio; Paolo Bruzzi; Paolo Spirito
Journal:  J Am Coll Cardiol       Date:  2002-11-20       Impact factor: 24.094

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  2 in total

Review 1.  Cardiomyopathy and pregnancy.

Authors:  Maria Schaufelberger
Journal:  Heart       Date:  2019-07-15       Impact factor: 5.994

2.  Brain natriuretic peptide in pregnant women with heart disease.

Authors:  Karanvir Singh; Pooja Sikka; Vanita Suri; Rishikesh Prasad; Madhu Khullar; Rajesh Vijayvergiya
Journal:  Obstet Med       Date:  2019-02-02
  2 in total

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