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Literature DB >> 2538645

Response of the human T-cell leukemia virus type 1 long terminal repeat to cyclic AMP.

H T Poteat¹, P Kadison, K McGuire, L Park, R E Park, J G Sodroski, W A Haseltine.

Abstract

The sequences that control transcriptional initiation of the provirus of the human T-cell leukemia virus type 1 (HTLV-1) are shown to be responsive to intracellular levels of cyclic AMP. A heptanucleotide sequence present within the 21-nucleotide repeat sequence that is similar to the cyclic AMP-responsive consensus (CRE) sequence was required for cyclic AMP-mediated increase in gene expression. Although the CRE-like sequences were contained within sequences that were responsive to the virally encoded trans-activator (tax), the evidence presented indicates that the mechanisms of promoter induction by the tax product and cyclic AMP are independent. The implication of cyclic AMP stimulation of HTLV-1 provirus gene expression for long-term persistence of infected T cells and for virus-induced transformation is discussed.

Entities: Chemical Disease Species

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Year: 1989 PMID： 2538645 PMCID： PMC248402

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

53 in total

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Authors: C Aussel; D Mary; J F Peyron; C Pelassy; B Ferrua; M Fehlmann
Journal: J Immunol Date: 1988-01-01 Impact factor: 5.422

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Authors: C A Rosen; J G Sodroski; W A Haseltine
Journal: Cell Date: 1985-07 Impact factor: 41.582

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Journal: Science Date: 1985-08-16 Impact factor: 47.728

4. Locus of inhibitory action of cAMP-dependent protein kinase in the antigen receptor-triggered cytotoxic T lymphocyte activation pathway.

Authors: H Takayama; G Trenn; M V Sitkovsky
Journal: J Biol Chem Date: 1988-02-15 Impact factor: 5.157

5. Rapid and efficient site-specific mutagenesis without phenotypic selection.

Authors: T A Kunkel; J D Roberts; R A Zakour
Journal: Methods Enzymol Date: 1987 Impact factor: 1.600

6. Functional activation of the long terminal repeat of human T-cell leukemia virus type I by a trans-acting factor.

Authors: J Fujisawa; M Seiki; T Kiyokawa; M Yoshida
Journal: Proc Natl Acad Sci U S A Date: 1985-04 Impact factor: 11.205

7. The p40x of human T-cell leukemia virus type I is a trans-acting activator of viral gene transcription.

Authors: M Seiki; J Inoue; T Takeda; A Hikikoshi; M Sato; M Yoshida
Journal: Jpn J Cancer Res Date: 1985-12

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Authors: R D Maca
Journal: Immunopharmacology Date: 1984-10

9. Location of cis-acting regulatory sequences in the human T-cell leukemia virus type I long terminal repeat.

Authors: C A Rosen; J G Sodroski; W A Haseltine
Journal: Proc Natl Acad Sci U S A Date: 1985-10 Impact factor: 11.205

10. The x gene is essential for HTLV replication.

Authors: I S Chen; D J Slamon; J D Rosenblatt; N P Shah; S G Quan; W Wachsman
Journal: Science Date: 1985-07-05 Impact factor: 47.728

33 in total

1. Interaction of the human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax with cellular factors that bind specifically to the 21-base-pair repeats in the HTLV-I enhancer.

Authors: L J Zhao; C Z Giam
Journal: Proc Natl Acad Sci U S A Date: 1991-12-15 Impact factor: 11.205

2. Protein kinase A-dependent binding of a nuclear factor to the 21-base-pair repeat of the human T-cell leukemia virus type I long terminal repeat.

Authors: H T Poteat; F Y Chen; P Kadison; J G Sodroski; W A Haseltine
Journal: J Virol Date: 1990-03 Impact factor: 5.103

Review 3. CRE-decoy oligonucleotide-inhibition of gene expression and tumor growth.

Authors: Y S Cho-Chung; Y G Park; M Nesterova; Y N Lee; Y S Cho
Journal: Mol Cell Biochem Date: 2000-09 Impact factor: 3.396

4. Upregulation of human T-cell leukemia virus type 1 antisense transcription by the viral tax protein.

Authors: Sébastien Landry; Marilène Halin; Amandine Vargas; Isabelle Lemasson; Jean-Michel Mesnard; Benoit Barbeau
Journal: J Virol Date: 2008-12-10 Impact factor: 5.103

5. T-cell receptor/CD28 engagement when combined with prostaglandin E2 treatment leads to potent activation of human T-cell leukemia virus type 1.

Authors: Nancy Dumais; Marie-Eve Paré; Simon Mercier; Salim Bounou; Susan J Marriot; Benoit Barbeau; Michel J Tremblay
Journal: J Virol Date: 2003-10 Impact factor: 5.103

6. Selective infection of human T-lymphotropic virus type 1 (HTLV-1)-infected cells by chimeric human immunodeficiency viruses containing HTLV-1 tax response elements in the long terminal repeat.

Authors: H C Lin; M Bodkin; R B Lal; A B Rabson
Journal: J Virol Date: 1995-11 Impact factor: 5.103

7. Isolation of cDNAs for DNA-binding proteins which specifically bind to a tax-responsive enhancer element in the long terminal repeat of human T-cell leukemia virus type I.

Authors: A Tsujimoto; H Nyunoya; T Morita; T Sato; K Shimotohno
Journal: J Virol Date: 1991-03 Impact factor: 5.103

8. Complex formation between CREB and Tax enhances the binding affinity of CREB for the human T-cell leukemia virus type 1 21-base-pair repeats.

Authors: M J Yin; R B Gaynor
Journal: Mol Cell Biol Date: 1996-06 Impact factor: 4.272

9. Human T-cell lymphotropic virus type 1 Tax1 activation of NF-kappa B: involvement of the protein kinase C pathway.

Authors: P F Lindholm; M Tamami; J Makowski; J N Brady
Journal: J Virol Date: 1996-04 Impact factor: 5.103

10. Human T-cell lymphotropic virus type I (HTLV-I) transcriptional activator, Tax, enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction.

Authors: L J Zhao; C Z Giam
Journal: Proc Natl Acad Sci U S A Date: 1992-08-01 Impact factor: 11.205