Literature DB >> 25386438

Case series of skin adnexal tumours.

V Rajalakshmi1, Sathish Selvakumar2, K Rajeswari2, K Meenakshisundaram3, Veena G4, Padmini Ramachandran4.   

Abstract

BACKGROUND: Skin adnexal tumours (SATs) are a large and diverse group of benign and malignant neoplasms. They are uncommon. They can be single or multiple, sporadic or familial and they might be markers for syndromes associated with internal malignancies. Benign adnexal tumours are more common and malignant SATs are rare and are locally aggressive and have the potential for nodal involvement and distant metastasis with a poor clinical outcome.Therefore recognition of SATs and establishing a diagnosis of malignancy in SATs is important for therapeutic and prognostic reasons. AIMS AND
OBJECTIVES: SATs are rare benign and malignant neoplasms. They are not commonly encountered in the routine surgical pathology practice.Hence this study aims at finding the frequency, clinical presentation and the histopathological appearances of SATS, and the differentiating features between benign and malignant tumours.
MATERIALS AND METHODS: This is partly a retrospective and partly a prospective study done in a tertiary care hospital over a period of four years .All the SATs reported during this period are analysed for their clinical features, age, sex incidence and their gross and histopathological features.
RESULTS: In the four years period 1,64,220 patients attended the hospital. The total number of SATS reported during this period were 21 cases (0.0128 %) Benign tumours were 19 (90.48%). Malignant tumours were 2(9.52%) The mean age for males 36.9 years and for females 35. Two years. There were 11 male patients and 10 female patients. Tumours of hair follicular differentiation were 7 (33.33%). Tumour like lesion of sebaceous origin was 1 (4.76%). Tumours of sweat gland origin were 11 (52.38%). Malignant tumours of eccrine origin were 2 (9.52%).
CONCLUSION: SATs are not common. Their incidence in our study is only 0.0128 % of all cases. Eventhough benign SATs are more common than the malignant tumours, malignant SATs can occur both in young and elderly patients and they are aggressive and the SATs should be excised with wide tumour free margins.

Entities:  

Keywords:  Adnexal; Benign; Gold Standard; Histopathology; Malignant; Skin

Year:  2014        PMID: 25386438      PMCID: PMC4225890          DOI: 10.7860/JCDR/2014/8710.4844

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  5 in total

Review 1.  Skin adnexal neoplasms--part 1: an approach to tumours of the pilosebaceous unit.

Authors:  K O Alsaad; N A Obaidat; D Ghazarian
Journal:  J Clin Pathol       Date:  2006-08-01       Impact factor: 3.411

Review 2.  Skin adnexal neoplasms--part 2: an approach to tumours of cutaneous sweat glands.

Authors:  Nidal A Obaidat; Khaled O Alsaad; Danny Ghazarian
Journal:  J Clin Pathol       Date:  2006-08-01       Impact factor: 3.411

3.  A clinico-histopathological study of appendageal skin tumors, affecting head and neck region in patients attending the dermatology opd of a tertiary care centre in eastern India.

Authors:  Abanti Saha; Nilay K Das; Ramesh C Gharami; Satyendra N Chowdhury; Pijush K Datta
Journal:  Indian J Dermatol       Date:  2011-01       Impact factor: 1.494

Review 4.  Cutaneous adnexal neoplasms.

Authors:  Craig A Storm; John T Seykora
Journal:  Am J Clin Pathol       Date:  2002-12       Impact factor: 2.493

5.  Benign vs. Malignant Skin Adnexal Neoplasms: How Useful are Silhouettes?

Authors:  Rajalakshmi Tirumalae; Mo Roopa
Journal:  Indian J Dermatol       Date:  2013-01       Impact factor: 1.494

  5 in total
  3 in total

1.  [Skin adnexal tumors: Histological study about 96 cases].

Authors:  Mohamed Réda El Ochi; Adil Boudhas; Mohammed Allaoui; Issam Rharrassi; Hafsa Chahdi; Abderrahman Al Bouzidi; Mohammed Oukabli
Journal:  Pan Afr Med J       Date:  2015-04-20

2.  Histopathological Analysis of Skin Adnexal Tumors: A Three Year Study of 110 Cases at A Tertiary Care Center.

Authors:  Kanwalpreet Kaur; Karuna Gupta; Deepika Hemrajani; Ajay Yadav; Kalpana Mangal
Journal:  Indian J Dermatol       Date:  2017 Jul-Aug       Impact factor: 1.494

3.  Are clinicians successful in diagnosing cutaneous adnexal tumors? a retrospective, clinicopathological study

Authors:  Melek Aslan Kayiran; Ayşe Serap Karadağ; Yasin Küçük; Bengü Çobanoğlu Şimşek; Vefa Asli Erdemir; Necmettin Akdeniz
Journal:  Turk J Med Sci       Date:  2020-06-23       Impact factor: 0.973

  3 in total

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