Literature DB >> 25386086

New strategies for prevention and treatment of splenic artery steal syndrome after liver transplantation.

Ji-Yong Song1, Bing-Yi Shi1, Zhi-Dong Zhu1, De-Hua Zheng1, Gang Li1, Li-Kui Feng1, Lin Zhou1, Tian-Tian Wu1, Guo-Sheng Du1.   

Abstract

AIM: To explore a prophylactic procedure to prevent splenic artery steal syndrome (SASS), as well as a therapeutic intervention to correct it.
METHODS: Forty-three liver transplant patients were enrolled in a non-randomized controlled trial, with the eligible criterion that the diameter of the splenic artery is more than 5 mm and/or 1.5 times of the diameter of the hepatic artery. The procedure of splenic artery banding was performed in 28 of the 43 patients, with the other 15 patients studied as a control group. SASS and other complications were compared between these two groups. A new therapeutic intervention, temporary incomplete blockade of the splenic artery with a balloon, was performed to treat SASS in this study.
RESULTS: The incidence of SASS was decreased by banding the splenic artery (0/28 vs 5/15, P = 0.006), and the same result was observed in total complications associated with prophylactic procedures (2/28 vs 6/15, P = 0.014). Five patients in the control group developed SASS within 5 d after OLT, 2 of whom were treated by coil embolization of the splenic artery, whereas the other 3 by temporary blockade of the splenic artery. Reappeared or better hepatic arteries with improved systolic amplitude and increased diastolic flow were detected by Doppler ultrasonography in all the 5 patients. Local splenic ischemic necrosis and nonanastomotic biliary stricture were diagnosed respectively in one patient treated by coil embolization, and no collateral complication was detected in patients treated by temporary blockade of the splenic artery.
CONCLUSION: SASS should be avoided during the operation by banding the splenic artery. Temporary blockade of the splenic artery is a new safe and effective intervention for SASS.

Entities:  

Keywords:  Angiography; Liver transplantation; Organ transplantation; Splenic artery steal syndrome; Vascular complication

Mesh:

Year:  2014        PMID: 25386086      PMCID: PMC4223271          DOI: 10.3748/wjg.v20.i41.15367

Source DB:  PubMed          Journal:  World J Gastroenterol        ISSN: 1007-9327            Impact factor:   5.742


  39 in total

1.  [Arterial steal syndrome in patients after liver transplantation: transarterial embolization of the splenic and gastroduodenal arteries].

Authors:  T J Vogl; W Pegios; J O Balzer; M Lobo; P Neuhaus
Journal:  Rofo       Date:  2001-10

2.  Splenic artery syndrome after orthotopic liver transplantation: treatment with the Amplatzer vascular plug.

Authors:  M H Maurer; M T Mogl; P Podrabsky; T Denecke; C Grieser; V Fröling; C Scheurig-Münkler; O Guckelberger; T J Kroencke
Journal:  Cardiovasc Intervent Radiol       Date:  2010-12-24       Impact factor: 2.740

3.  The arterial anastomosis in liver transplantation: complications, treatment and outcome.

Authors:  Monika Pakosz-Golanowsha; Jerzy Lubikowski; Mariola Post; Konrad Jarosz; Katarzyna Zasada-Cedro; Piotr Milkiewicz; Maciej Wójcicki
Journal:  Hepatogastroenterology       Date:  2010 Nov-Dec

Review 4.  Splenic arterial interventions: anatomy, indications, technical considerations, and potential complications.

Authors:  David C Madoff; Alban Denys; Michael J Wallace; Ravi Murthy; Sanjay Gupta; Edmund P Pillsbury; Kamran Ahrar; Bertrand Bessoud; Marshall E Hicks
Journal:  Radiographics       Date:  2005-10       Impact factor: 5.333

5.  Abnormal splenic artery diameter/hepatic artery diameter ratio in cirrhosis-induced portal hypertension.

Authors:  Dao-Bing Zeng; Chuan-Zhou Dai; Shi-Chun Lu; Ning He; Wei Wang; Hong-Jun Li
Journal:  World J Gastroenterol       Date:  2013-02-28       Impact factor: 5.742

6.  Doppler evaluation of arterial complications of adult orthotopic liver transplantation.

Authors:  Alessandro Vit; Alessandro De Candia; Giuseppe Como; Chiara Del Frate; Andrea Marzio; Massimo Bazzocchi
Journal:  J Clin Ultrasound       Date:  2003-09       Impact factor: 0.910

7.  Multidetector computed tomographic angiography findings of splenic artery steal syndrome in liver transplantation.

Authors:  I Kirbas; E M K Ulu; A Ozturk; M Coskun; A Harman; E Ogus; M Haberal
Journal:  Transplant Proc       Date:  2007-05       Impact factor: 1.066

8.  Splenic embolization in liver transplant recipients: early outcomes.

Authors:  C P Chao; J H Nguyen; R Paz-Fumagalli; M K Dougherty; A H Stockland
Journal:  Transplant Proc       Date:  2007-12       Impact factor: 1.066

9.  Splenic artery steal syndrome in living donor liver transplantation: a case report.

Authors:  K Shimizu; H Tashiro; Y Fudaba; T Itamoto; H Ohdan; S Fukuda; N Toyota; H Kakizawa; Y Ushitora; T Ogawa; T Asahara
Journal:  Transplant Proc       Date:  2007-12       Impact factor: 1.066

10.  Reactive metabolites and AGE-RAGE-mediated inflammation in patients following liver transplantation.

Authors:  Thorsten Brenner; Thomas H Fleming; David Spranz; Peter Schemmer; Thomas Bruckner; Florian Uhle; Eike O Martin; Markus A Weigand; Stefan Hofer
Journal:  Mediators Inflamm       Date:  2013-05-22       Impact factor: 4.711

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