Literature DB >> 25385930

Pediatric Provider Insight Into Newborn Screening for Glucose-6-Phosphate Dehydrogenase Deficiency.

Janine Bernardo1, Mary Nock2.   

Abstract

OBJECTIVE: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a major contributor to neonatal hyperbilirubinemia, yet newborn screening for this disorder in the United States is not standard practice. We surveyed pediatric providers regarding a novel newborn G6PD screening program successfully implemented in 2007 at a US urban women's hospital newborn nursery. STUDY
DESIGN: An electronic survey was distributed to 472 pediatric providers addressing extent to which they were influenced by the screening program.
RESULTS: Ninety-two (20%) providers responded, of whom 74 (80%) had taken care of G6PD-deficient patients diagnosed by the screening program. A majority found the diagnosis helpful for patient management and influential in their management. Most common changes in management included more counseling on jaundice and follow-up and avoidance of hemolytic crisis triggers.
CONCLUSIONS: General pediatric providers support newborn G6PD screening and appreciate the current program. Knowing the G6PD deficiency status of newborns informed and influenced pediatric providers' care.
© The Author(s) 2014.

Entities:  

Keywords:  glucose-6-phosphate dehydrogenase deficiency; hyperbilirubinemia; management; neonatal; screening

Mesh:

Year:  2014        PMID: 25385930      PMCID: PMC4946335          DOI: 10.1177/0009922814557786

Source DB:  PubMed          Journal:  Clin Pediatr (Phila)        ISSN: 0009-9228            Impact factor:   1.168


  23 in total

1.  Does familiarity breed acceptance? The influence of policy on physicians' attitudes toward newborn screening programs.

Authors:  Joy Koopmans; Lainie Friedman Ross
Journal:  Pediatrics       Date:  2006-05       Impact factor: 7.124

2.  Newborn screening in the Asia Pacific region.

Authors:  Carmencita D Padilla; Bradford L Therrell
Journal:  J Inherit Metab Dis       Date:  2007-07-23       Impact factor: 4.982

Review 3.  A global need for affordable neonatal jaundice technologies.

Authors:  Tina M Slusher; Alvin Zipursky; Vinod K Bhutani
Journal:  Semin Perinatol       Date:  2011-06       Impact factor: 3.300

4.  Marked decline of favism after neonatal glucose-6-phosphate dehydrogenase screening and health education: the northern Sardinian experience.

Authors:  T Meloni; G Forteleoni; G F Meloni
Journal:  Acta Haematol       Date:  1992       Impact factor: 2.195

5.  Neonatal screening for glucose-6-phosphate dehydrogenase deficiency.

Authors:  Mritunjay Pao; Anjali Kulkarni; Vidya Gupta; Sushma Kaul; Saroja Balan
Journal:  Indian J Pediatr       Date:  2005-10       Impact factor: 1.967

Review 6.  G6PD: population genetics and clinical manifestations.

Authors:  E Beutler
Journal:  Blood Rev       Date:  1996-03       Impact factor: 8.250

7.  The need for neonatal glucose-6-phosphate dehydrogenase screening: a global perspective.

Authors:  M Kaplan; C Hammerman
Journal:  J Perinatol       Date:  2009-02       Impact factor: 2.521

Review 8.  Kernicterus: epidemiological strategies for its prevention through systems-based approaches.

Authors:  Vinod K Bhutani; Lois H Johnson; M Jeffrey Maisels; Thomas B Newman; Ciaran Phibbs; Ann R Stark; Marshalyn Yeargin-Allsopp
Journal:  J Perinatol       Date:  2004-10       Impact factor: 2.521

9.  Screening for glucose-6-phosphate dehydrogenase deficiency can prevent severe neonatal jaundice.

Authors:  A A Mallouh; G Imseeh; Y K Abu-Osba; J A Hamdan
Journal:  Ann Trop Paediatr       Date:  1992

Review 10.  Identification of neonates at risk for hazardous hyperbilirubinemia: emerging clinical insights.

Authors:  Jon F Watchko
Journal:  Pediatr Clin North Am       Date:  2009-06       Impact factor: 3.278

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  3 in total

1.  Newborn Screening for Congenital Hypothyroidism, Congenital Adrenal Hyperplasia, and Glucose-6-Phosphate Dehydrogenase Deficiency for Improving Health Care in India.

Authors:  Jyotsna Verma; Papai Roy; Divya C Thomas; Geetu Jhingan; Azad Singh; Sunita Bijarnia-Mahay; Ishwar C Verma
Journal:  J Pediatr Intensive Care       Date:  2019-10-14

2.  The Newborn Screening Quality Assurance Program at the Centers for Disease Control and Prevention: Thirty-five Year Experience Assuring Newborn Screening Laboratory Quality.

Authors:  Víctor R De Jesús; Joanne V Mei; Suzanne K Cordovado; Carla D Cuthbert
Journal:  Int J Neonatal Screen       Date:  2015

Review 3.  Point-of-Care Testing for G6PD Deficiency: Opportunities for Screening.

Authors:  Athena Anderle; Germana Bancone; Gonzalo J Domingo; Emily Gerth-Guyette; Sampa Pal; Ari W Satyagraha
Journal:  Int J Neonatal Screen       Date:  2018-11-19
  3 in total

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