BACKGROUND: Trait anger consists of affective, behavioral, and cognitive (ABC) dimensions and may increase vulnerability for interpersonal conflict, diminished social support, and greater psychological distress. The concurrent influence of anger and psychosocial dysfunction on Human Immunodeficiency Virus (HIV) disease severity is unknown. PURPOSE: The purpose of this study was to examine plausible psychosocial avenues (e.g., coping, social support, psychological distress), whereby trait anger may indirectly influence HIV disease status. METHODS: Three hundred seventy-seven HIV seropositive adults, aged 18-55 years (58% AIDS-defined), completed a battery of psychosocial surveys and provided a fasting blood sample for HIV-1 viral load and T lymphocyte count assay. RESULTS: A second-order factor model confirmed higher levels of the multidimensional anger trait, which was directly associated with elevated psychological distress and avoidant coping (p<.001) and indirectly associated with greater HIV disease severity (p<.01) (comparative fit index (CFI)=0.90, root-mean-square error of approximation (RMSEA)=0.06, standardized root-mean-square residual (SRMR)=0.06). CONCLUSION: The model supports a role for the ABC components of anger, which may negatively influence immune function through various psychosocial mechanisms; however, longitudinal study is needed to elucidate these effects.
BACKGROUND: Trait anger consists of affective, behavioral, and cognitive (ABC) dimensions and may increase vulnerability for interpersonal conflict, diminished social support, and greater psychological distress. The concurrent influence of anger and psychosocial dysfunction on Human Immunodeficiency Virus (HIV) disease severity is unknown. PURPOSE: The purpose of this study was to examine plausible psychosocial avenues (e.g., coping, social support, psychological distress), whereby trait anger may indirectly influence HIV disease status. METHODS: Three hundred seventy-seven HIV seropositive adults, aged 18-55 years (58% AIDS-defined), completed a battery of psychosocial surveys and provided a fasting blood sample for HIV-1 viral load and T lymphocyte count assay. RESULTS: A second-order factor model confirmed higher levels of the multidimensional anger trait, which was directly associated with elevated psychological distress and avoidant coping (p<.001) and indirectly associated with greater HIV disease severity (p<.01) (comparative fit index (CFI)=0.90, root-mean-square error of approximation (RMSEA)=0.06, standardized root-mean-square residual (SRMR)=0.06). CONCLUSION: The model supports a role for the ABC components of anger, which may negatively influence immune function through various psychosocial mechanisms; however, longitudinal study is needed to elucidate these effects.
Authors: Frank J Penedo; Jeffrey S Gonzalez; Jason R Dahn; Mike Antoni; Robert Malow; Paul Costa; Neil Schneiderman Journal: J Psychosom Res Date: 2003-03 Impact factor: 3.006
Authors: Sarosh J Motivala; Barry E Hurwitz; Maria M Llabre; Nancy G Klimas; Mary Ann Fletcher; Michael H Antoni; William G LeBlanc; Neil Schneiderman Journal: Psychosom Med Date: 2003 Jul-Aug Impact factor: 4.312
Authors: Frank J Penedo; Jeffrey S Gonzalez; Catherine Davis; Jason Dahn; Michael H Antoni; Gail Ironson; Robert Malow; Neil Schneiderman Journal: Ann Behav Med Date: 2003
Authors: Jeffrey S Gonzalez; Frank J Penedo; Maria M Llabre; Ron E Durán; Michael H Antoni; Neil Schneiderman; Rob Horne Journal: Ann Behav Med Date: 2007-08
Authors: Roger C McIntosh; Michael Antoni; Adam Carrico; Ron Duran; Barry E Hurwitz; Gail Ironson; Mary Ann Fletcher; Nancy Klimas; Mahendra Kumar; Neil Schneiderman Journal: J Behav Med Date: 2017-02-02
Authors: Roger C McIntosh; Gail Ironson; Michael Antoni; Betty Lai; Mahendra Kumar; Mary Ann Fletcher; Neil Schneiderman Journal: Int J Behav Med Date: 2017-04
Authors: Rebecca B Hershow; H Luz McNaughton Reyes; Tran Viet Ha; Geetanjali Chander; Nguyen Vu Tuyet Mai; Teerada Sripaipan; Constantine Frangakis; David W Dowdy; Carl Latkin; Heidi E Hutton; Audrey Pettifor; Suzanne Maman; Vivian F Go Journal: Drug Alcohol Depend Date: 2020-06-10 Impact factor: 4.492