Literature DB >> 2538352

Molecular cloning and sequencing of human cDNA for phosphoribosyl pyrophosphate synthetase subunit II.

T Iizasa1, M Taira, H Shimada, S Ishijima, M Tatibana.   

Abstract

cDNA clones for human phosphoribosyl pyrophosphate synthetase subunit II (PRS II) were isolated. The five overlapping clones contained 2457 base pairs (bp) covering a 954-bp complete coding region for 318 amino acid residues. Homologies between human and rat PRS II were 99% of the amino acids and 88% of the nucleotides in the coding region. This amino acid homology seems to be the highest so far reported for enzymes involved in nucleotide metabolism and glycolysis. The highly conserved structure may be required for unique catalysis and rigid regulation of this enzyme.

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Year:  1989        PMID： 2538352     DOI： 10.1016/0014-5793(89)81159-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  9 in total

1.  Cloning of two distinct copies of human phosphoribosylpyrophosphate synthetase cDNA.

Authors:  B J Roessler; G Bell; S Heidler; S Seino; M Becker; T D Palella
Journal:  Nucleic Acids Res       Date:  1990-01-11       Impact factor: 16.971

2.  Complete cDNA sequence of rat phosphoribosylpyrophosphate synthetase subunit II (PRS II).

Authors:  S Ishijima; M Taira; M Tatibana
Journal:  Nucleic Acids Res       Date:  1989-11-11       Impact factor: 16.971

3.  Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site.

Authors:  Sheng Li; Yongcheng Lu; Baozhen Peng; Jianping Ding
Journal:  Biochem J       Date:  2007-01-01       Impact factor: 3.857

4.  The virulence gene cluster of Listeria monocytogenes is also present in Listeria ivanovii, an animal pathogen, and Listeria seeligeri, a nonpathogenic species.

Authors:  E Gouin; J Mengaud; P Cossart
Journal:  Infect Immun       Date:  1994-08       Impact factor: 3.441

5.  The genetic and functional basis of purine nucleotide feedback-resistant phosphoribosylpyrophosphate synthetase superactivity.

Authors:  M A Becker; P R Smith; W Taylor; R Mustafi; R L Switzer
Journal:  J Clin Invest       Date:  1995-11       Impact factor: 14.808

6.  Mammalian gene evolution: nucleotide sequence divergence between mouse and rat.

Authors:  K H Wolfe; P M Sharp
Journal:  J Mol Evol       Date:  1993-10       Impact factor: 2.395

7.  Organellar and cytosolic localization of four phosphoribosyl diphosphate synthase isozymes in spinach.

Authors:  B N Krath; B Hove-Jensen
Journal:  Plant Physiol       Date:  1999-02       Impact factor: 8.340

8.  Linkage of phosphoribosylpyrophosphate synthetases 1 and 2, Prps1 and Prps2, on the mouse X chromosome.

Authors:  K Lee; B Keitz; M Taira; V M Chapman
Journal:  Mamm Genome       Date:  1994-10       Impact factor: 2.957

Review 9.  Contribution of Model Organisms to Investigating the Far-Reaching Consequences of PRPP Metabolism on Human Health and Well-Being.

Authors:  Eziuche A Ugbogu; Lilian M Schweizer; Michael Schweizer
Journal:  Cells       Date:  2022-06-13       Impact factor: 7.666
  9 in total

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