Literature DB >> 2538263

Transcatheter arterial embolization using iodized oil (lipiodol) mixed with an anticancer drug for the treatment of hepatocellular carcinoma.

H Ohishi1, H Yoshimura, H Uchida, H Sakaguchi, T Yoshioka, S Ohue, T Matsui, A Takaya, T Tsujii.   

Abstract

The therapeutic results of Lp-TAE (transcatheter arterial embolization with Gelfoam particles preceded by the infusion of a mixture of lipiodol and an anticancer drug via the proper hepatic artery) were evaluated in hepatocellular carcinomas (523 non-resected and 24 resected cases). Excellent therapeutic effects were confirmed not only for the main tumor but also for the daughter nodules by a histological examination of the liver tissues resected after Lp-TAE. The cumulative 1-year, 2-year and 3-year survival rates in the 523 non-resected cases were 60.4%, 42.9% and 28.0% respectively. These survival rates were all higher than those achieved by Gelfoam TAE. The above results suggest the usefulness of Lp-TAE in the treatment of hepatocellular carcinoma.

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Year:  1989        PMID： 2538263     DOI： 10.1007/bf00647236

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN： 0344-5704            Impact factor:   3.333


  6 in total

1.  Treatment of hepatocellular carcinoma by transarterial injection of anticancer agents in iodized oil suspension or of radioactive iodized oil solution.

Authors:  H Kobayashi; H Hidaka; Y Kajiya; P Tanoue; H Inoue; K Ikeda; M Nakajo; S Shinohara
Journal:  Acta Radiol Diagn (Stockh)       Date:  1986 Mar-Apr

2.  Effect of arterial administration of high-molecular-weight anticancer agent SMANCS with lipid lymphographic agent on hepatoma: a preliminary report.

Authors:  T Konno; H Maeda; K Iwai; S Tashiro; S Maki; T Morinaga; M Mochinaga; T Hiraoka; I Yokoyama
Journal:  Eur J Cancer Clin Oncol       Date:  1983-08

3.  Hepatocellular carcinoma: treatment with intraarterial iodized oil with and without chemotherapeutic agents.

Authors:  K Takayasu; Y Shima; Y Muramatsu; N Moriyama; T Yamada; M Makuuchi; H Hasegawa; S Hirohashi
Journal:  Radiology       Date:  1987-05       Impact factor: 11.105

4.  Hepatocellular carcinoma detected by iodized oil.

Authors:  Y Yumoto; K Jinno; K Tokuyama; Y Araki; T Ishimitsu; H Maeda; T Konno; S Iwamoto; K Ohnishi; K Okuda
Journal:  Radiology       Date:  1985-01       Impact factor: 11.105

5.  Hepatocellular carcinoma detected by iodized oil. Use of anticancer agents.

Authors:  H Ohishi; H Uchida; H Yoshimura; S Ohue; J Ueda; M Katsuragi; N Matsuo; Y Hosogi
Journal:  Radiology       Date:  1985-01       Impact factor: 11.105

6.  Selective effects of Lipiodolized antitumor agents.

Authors:  T Kanematsu; K Inokuchi; K Sugimachi; T Furuta; T Sonoda; S Tamura; K Hasuo
Journal:  J Surg Oncol       Date:  1984-03       Impact factor: 3.454
  6 in total
  6 in total

1.  Transcatheter hepatic segmental arterial embolization using lipiodol mixed with an anticancer drug and Gelfoam particles for hepatocellular carcinoma.

Authors:  H Uchida; H Ohishi; N Matsuo; K Nishimine; S Ohue; Y Nishimura; M Maeda; T Yoshioka
Journal:  Cardiovasc Intervent Radiol       Date:  1990 Jun-Jul       Impact factor: 2.740

2.  Prospective and randomized clinical trial for the treatment of hepatocellular carcinoma--a comparison of lipiodol-transcatheter arterial embolization with and without adriamycin (first cooperative study). The Cooperative Study Group for Liver Cancer Treatment of Japan.

Authors:  S Kawai; J Okamura; M Ogawa; Y Ohashi; M Tani; J Inoue; Y Kawarada; M Kusano; Y Kubo; C Kuroda
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

3.  Effective segmental chemoembolization of advanced hepatocellular carcinoma with tumor thrombus in the portal vein.

Authors:  T Katsumori; M Fujita; T Takahashi; O Satoh; S Ichijima; T Nakamura; H Morishita; K Ohno; Y Nakano; T Maeda
Journal:  Cardiovasc Intervent Radiol       Date:  1995 Jul-Aug       Impact factor: 2.740

Review 4.  Chemo-occlusion for the treatment of liver cancer. A new technique using degradable starch microspheres.

Authors:  T Taguchi
Journal:  Clin Pharmacokinet       Date:  1994-04       Impact factor: 6.447

5.  Segmental transarterial chemoembolization with Lipiodol mixed with anticancer drugs for nonresectable hepatocellular carcinoma: follow-up CT and therapeutic results.

Authors:  K Nishimine; H Uchida; N Matsuo; H Sakaguchi; S Hirohashi; Y Nishimura; Q Guo; H Ohishi; N Nagano; T Yoshioka
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333

6.  Prospective and randomized controlled study of chemoembolization therapy in patients with advanced hepatocellular carcinoma. Cooperative Study Group for Liver Cancer Treatment in Shikoku area.

Authors:  S Watanabe; M Nishioka; Y Ohta; N Ogawa; S Ito; Y Yamamoto
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333
  6 in total

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