Literature DB >> 25382559

Drug development for controlling Ebola epidemic - a race against time.

Jianjun Gao1, Lin Yin.   

Abstract

The Ebola outbreak in West Africa this year is causing global panic. The high mortality of this disease is largely due to lack of effective preventive vaccines or therapeutic drugs. Realizing the gravity and urgency in controlling the epidemic, governments and drug companies across the world have taken many strong measures to speed up the process of drug development. Several representative candidate drugs that demonstrate potent anti-Ebola activity in preclinical studies have been pushed forward to higher research stages to obtain an earlier official license. It is expected that proven preventive or therapeutic regimens could be established in the near future.

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Year:  2014        PMID: 25382559     DOI: 10.5582/ddt.2014.01040

Source DB:  PubMed          Journal:  Drug Discov Ther        ISSN: 1881-7831


  9 in total

Review 1.  Backs against the wall: novel and existing strategies used during the 2014-2015 Ebola virus outbreak.

Authors:  Gary Wong; Gary P Kobinger
Journal:  Clin Microbiol Rev       Date:  2015-07       Impact factor: 26.132

2.  Oral delivery of therapeutic proteins bioencapsulated in plant cells: preclinical and clinical advances.

Authors:  Imran Khan; Henry Daniell
Journal:  Curr Opin Colloid Interface Sci       Date:  2021-03-24       Impact factor: 8.209

Review 3.  Ebola and the need for restructuring pharmaceutical incentives.

Authors:  Abraar Karan; Thomas Pogge
Journal:  J Glob Health       Date:  2015-06       Impact factor: 4.413

4.  Contrasting academic and lay press print coverage of the 2013-2016 Ebola Virus Disease outbreak.

Authors:  Mark D Kieh; Elim M Cho; Ian A Myles
Journal:  PLoS One       Date:  2017-06-22       Impact factor: 3.240

5.  Assessing Ebola-related web search behaviour: insights and implications from an analytical study of Google Trends-based query volumes.

Authors:  Cristiano Alicino; Nicola Luigi Bragazzi; Valeria Faccio; Daniela Amicizia; Donatella Panatto; Roberto Gasparini; Giancarlo Icardi; Andrea Orsi
Journal:  Infect Dis Poverty       Date:  2015-12-10       Impact factor: 4.520

6.  Ebola Virus Infection: Overview and Update on Prevention and Treatment.

Authors:  Miguel J Martínez; Abdulbaset M Salim; Juan C Hurtado; Paul E Kilgore
Journal:  Infect Dis Ther       Date:  2015-09-12

Review 7.  Oral Delivery of Protein Drugs Bioencapsulated in Plant Cells.

Authors:  Kwang-Chul Kwon; Henry Daniell
Journal:  Mol Ther       Date:  2016-06-06       Impact factor: 11.454

Review 8.  Discovering Drugs for the Treatment of Ebola Virus.

Authors:  Sandra L Bixler; Allen J Duplantier; Sina Bavari
Journal:  Curr Treat Options Infect Dis       Date:  2017-08-04

Review 9.  Advances in Designing and Developing Vaccines, Drugs, and Therapies to Counter Ebola Virus.

Authors:  Kuldeep Dhama; Kumaragurubaran Karthik; Rekha Khandia; Sandip Chakraborty; Ashok Munjal; Shyma K Latheef; Deepak Kumar; Muthannan Andavar Ramakrishnan; Yashpal Singh Malik; Rajendra Singh; Satya Veer Singh Malik; Raj Kumar Singh; Wanpen Chaicumpa
Journal:  Front Immunol       Date:  2018-08-10       Impact factor: 7.561

  9 in total

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