PURPOSE: Patients' perception of health-related quality of life (HRQOL) is a consistent and powerful predictor of the outcome of end-stage renal disease (ESRD) patients under dialysis. This study aims to identify factors that could affect the HRQOL of ESRD patients under online hemodiafiltration (OL-HDF). METHODS: We evaluated 322 ESRD patients under OL-HDF (59.63% males; 64.9 ± 14.3 years old) from five dialysis units in the north of Portugal. Socio-demographic data, comorbidities, hematological data, iron status, dialysis adequacy, nutritional and inflammatory markers were collected from patients records. Patient's reported HRQOL score was assessed by using the Kidney Disease Quality of Life-Short Form (KDQOL-SF). RESULTS: ESRD patients showed a mean (± SD) of 53.17% (± 15.31%) in SF-36 total score, 50.17% (± 9.51%) in the SF-36 mental component summary (MCS) and 49.75% (± 9.44%) in the SF-36 physical component summary (PCS). Red cell distribution width (RDW), feminine gender and diabetes were found as significant predictors of SF-36 total score of HRQOL, which accounts for 12% of the total explained variance. Patient satisfaction, RDW, body mass index and gender were identified as predictors for the PCS, which accounts for 22% of total explained variance. Furthermore, patient satisfaction and dry weight were found as predictors for MCS. These predictors accounted for 28% of the total explained variance. CONCLUSIONS: Our results showed that the coexistence of diabetes, gender and erythropoietic disturbances are predictors of HRQOL in patients under OL-HDF and suggest that more attention should be given to woman patients, to the improvement of anemia and to diabetic patients, who are more prone to perceive a worst HRQOL.
PURPOSE:Patients' perception of health-related quality of life (HRQOL) is a consistent and powerful predictor of the outcome of end-stage renal disease (ESRD) patients under dialysis. This study aims to identify factors that could affect the HRQOL of ESRDpatients under online hemodiafiltration (OL-HDF). METHODS: We evaluated 322 ESRDpatients under OL-HDF (59.63% males; 64.9 ± 14.3 years old) from five dialysis units in the north of Portugal. Socio-demographic data, comorbidities, hematological data, iron status, dialysis adequacy, nutritional and inflammatory markers were collected from patients records. Patient's reported HRQOL score was assessed by using the Kidney Disease Quality of Life-Short Form (KDQOL-SF). RESULTS:ESRDpatients showed a mean (± SD) of 53.17% (± 15.31%) in SF-36 total score, 50.17% (± 9.51%) in the SF-36 mental component summary (MCS) and 49.75% (± 9.44%) in the SF-36 physical component summary (PCS). Red cell distribution width (RDW), feminine gender and diabetes were found as significant predictors of SF-36 total score of HRQOL, which accounts for 12% of the total explained variance. Patient satisfaction, RDW, body mass index and gender were identified as predictors for the PCS, which accounts for 22% of total explained variance. Furthermore, patient satisfaction and dry weight were found as predictors for MCS. These predictors accounted for 28% of the total explained variance. CONCLUSIONS: Our results showed that the coexistence of diabetes, gender and erythropoietic disturbances are predictors of HRQOL in patients under OL-HDF and suggest that more attention should be given to womanpatients, to the improvement of anemia and to diabeticpatients, who are more prone to perceive a worst HRQOL.
Authors: Kamyar Kalantar-Zadeh; Kevin C Abbott; Abdulla K Salahudeen; Ryan D Kilpatrick; Tamara B Horwich Journal: Am J Clin Nutr Date: 2005-03 Impact factor: 7.045
Authors: Alberto Martínez-Castelao; José Luis Gòrriz; Fernando Garcia-López; Katia López-Revuelta; Fernando De Alvaro; Josep M Cruzado Journal: J Nephrol Date: 2004 Jul-Aug Impact factor: 3.902
Authors: P L Kimmel; R A Peterson; K L Weihs; S J Simmens; D H Boyle; D Verme; W O Umana; J H Veis; S Alleyne; I Cruz Journal: J Am Soc Nephrol Date: 1995-04 Impact factor: 10.121
Authors: Edward Zimbudzi; Clement Lo; Sanjeeva Ranasinha; Martin Gallagher; Gregory Fulcher; Peter G Kerr; Grant Russell; Helena Teede; Tim Usherwood; Rowan Walker; Sophia Zoungas Journal: PLoS One Date: 2016-12-19 Impact factor: 3.240
Authors: Robin W M Vernooij; Michiel L Bots; Giovanni F M Strippoli; Bernard Canaud; Krister Cromm; Mark Woodward; Peter J Blankestijn Journal: Nephrol Dial Transplant Date: 2022-05-25 Impact factor: 7.186
Authors: Sahbanathul Missiriya Jalal; Mini Rani Mary Beth; Zahra Mohammed Bo Khamseen Journal: Int J Environ Res Public Health Date: 2022-08-07 Impact factor: 4.614
Authors: Sarah Elshahat; Paul Cockwell; Alexander P Maxwell; Matthew Griffin; Timothy O'Brien; Ciaran O'Neill Journal: PLoS One Date: 2020-03-24 Impact factor: 3.240