Literature DB >> 25380610

The emergent reversal of coagulopathies encountered in neurosurgery and neurology: a technical note.

Joshua Eric Medow1, Matthew R Dierks2, Eliot Williams3, J Christopher Zacko4.   

Abstract

It is imperative for neurologists, neurosurgeons, and neurointensivists to know how to stop life-threatening hemorrhage in both surgical and non-surgical patients. However, knowing how to medically correct a coagulopathy has become increasingly challenging as more contemporary and sophisticated anticoagulation agents are developed and prescribed. In a time-sensitive and life-threatening situation, where there is little margin for error, the neurosurgeon may not have ready access to information about the drug or condition that caused the coagulopathy or the information on how to treat it. This thorough review of the literature provides a comprehensive overview of the medications and conditions that can lead to persistent and/or life-threatening intracranial hemorrhage.
© 2015 Marshfield Clinic.

Entities:  

Keywords:  Anticoagulants; Coagulopathy; Intracerebral hemorrhage; Neurosurgery; Reversal

Mesh:

Year:  2014        PMID: 25380610      PMCID: PMC4435082          DOI: 10.3121/cmr.2014.1237

Source DB:  PubMed          Journal:  Clin Med Res        ISSN: 1539-4182


  19 in total

Review 1.  Parenteral anticoagulants: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Authors:  David A Garcia; Trevor P Baglin; Jeffrey I Weitz; Meyer Michel Samama
Journal:  Chest       Date:  2012-02       Impact factor: 9.410

Review 2.  Oral anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Authors:  Walter Ageno; Alexander S Gallus; Ann Wittkowsky; Mark Crowther; Elaine M Hylek; Gualtiero Palareti
Journal:  Chest       Date:  2012-02       Impact factor: 9.410

Review 3.  Ticagrelor: a review of its use in the management of acute coronary syndromes.

Authors:  Emma D Deeks
Journal:  Drugs       Date:  2011-05-07       Impact factor: 9.546

4.  Management of dabigatran-associated intracerebral and intraventricular hemorrhage: a case report.

Authors:  Andrew C Faust; Evan J Peterson
Journal:  J Emerg Med       Date:  2014-02-06       Impact factor: 1.484

Review 5.  Dabigatran etexilate--a novel, reversible, oral direct thrombin inhibitor: interpretation of coagulation assays and reversal of anticoagulant activity.

Authors:  Joanne van Ryn; Joachim Stangier; Sebastian Haertter; Karl-Heinz Liesenfeld; Wolfgang Wienen; Martin Feuring; Andreas Clemens
Journal:  Thromb Haemost       Date:  2010-03-29       Impact factor: 5.249

Review 6.  New-generation oral anticoagulants for the prevention of stroke: implications for neurosurgery.

Authors:  Tarek Y El Ahmadieh; Salah G Aoun; Marc R Daou; Najib E El Tecle; Rudy J Rahme; Randall B Graham; Joseph G Adel; H Hunt Batjer; Bernard R Bendok
Journal:  J Clin Neurosci       Date:  2013-07-05       Impact factor: 1.961

7.  Hemostatic therapy in experimental intracerebral hemorrhage associated with the direct thrombin inhibitor dabigatran.

Authors:  Wei Zhou; Sönke Schwarting; Sergio Illanes; Arthur Liesz; Moritz Middelhoff; Markus Zorn; Martin Bendszus; Sabine Heiland; Joanne van Ryn; Roland Veltkamp
Journal:  Stroke       Date:  2011-10-13       Impact factor: 7.914

8.  Rapid reversal of coagulopathy in warfarin-related intracranial haemorrhages with prothrombin complex concentrates.

Authors:  C T Chong; T W K Lew; P Kuperan; J J E Tan; H L Tan; T K Kwek
Journal:  Anaesth Intensive Care       Date:  2010-05       Impact factor: 1.669

9.  Treatments for reversing warfarin anticoagulation in patients with acute intracranial hemorrhage: a structured literature review.

Authors:  Brett F Bechtel; Timothy C Nunez; Jennifer A Lyon; Bryan A Cotton; Tyler W Barrett
Journal:  Int J Emerg Med       Date:  2011-07-08

10.  Variability in response to cryoprecipitate treatment for hemostatic defects in uremia.

Authors:  D J Triulzi; N Blumberg
Journal:  Yale J Biol Med       Date:  1990 Jan-Feb
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  2 in total

1.  Spontaneous hemorrhage after external ventricular drain placement in the setting of low factor VII secondary to liver cirrhosis.

Authors:  Melissa Ming Jie Chua; Alvin S Das; Julie Aurore Losman; Nirav J Patel; Saef Izzy
Journal:  Surg Neurol Int       Date:  2020-11-25

2.  Approach to the Coagulopathic Patient in the Intensive Care Unit.

Authors:  Manoj Yogendra Singh
Journal:  Indian J Crit Care Med       Date:  2019-09
  2 in total

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