Reem Z Sharaiha 1 , Prashant Kedia 1 , Nikhil Kumta 1 , Ersilia M DeFilippis 1 , Monica Gaidhane 1 , Alpana Shukla 1 , Louis J Aronne 1 , Michel Kahaleh 1 Show Affiliations »
Abstract
BACKGROUND AND AIMS: Novel endoscopic techniques have been developed as effective treatments for obesity. Recently, reduction of gastric volume via endoscopic placement of full-thickness sutures, termed endoscopic sleeve gastroplasty (ESG), has been described. Our aim was to evaluate the safety, technical feasibility, and clinical outcomes for ESG. PATIENT AND METHODS: Between August 2013 and May 2014, ESG was performed on 10 patients using an endoscopic suturing device. Their weight loss, waist circumference, and clinical outcomes were assessed. RESULTS: Mean patient age was 43.7 years and mean body mass index (BMI) was 45.2 kg/m(2). There were no significant adverse events noted. After 1 month, 3 months, and 6 months, excess weight loss of 18 %, 26 %, and 30 %, and mean weight loss of 11.5 kg, 19.4 kg, and 33.0 kg, respectively, were observed. The differences observed in mean BMI and waist circumference were 4.9 kg/m(2) (P = 0.0004) and 21.7 cm (P = 0.003), respectively. CONCLUSIONS: ESG is effective in achieving weight loss with minimal adverse events. This approach may provide a cost-effective outpatient procedure to add to the steadily growing armamentarium available for treatment of this significant epidemic. © Georg Thieme Verlag KG Stuttgart · New York.
BACKGROUND AND AIMS: Novel endoscopic techniques have been developed as effective treatments for obesity . Recently, reduction of gastric volume via endoscopic placement of full-thickness sutures, termed endoscopic sleeve gastroplasty (ESG), has been described. Our aim was to evaluate the safety, technical feasibility, and clinical outcomes for ESG. PATIENT AND METHODS: Between August 2013 and May 2014, ESG was performed on 10 patients using an endoscopic suturing device. Their weight loss , waist circumference, and clinical outcomes were assessed. RESULTS: Mean patient age was 43.7 years and mean body mass index (BMI) was 45.2 kg/m(2). There were no significant adverse events noted. After 1 month, 3 months, and 6 months, excess weight loss of 18 %, 26 %, and 30 %, and mean weight loss of 11.5 kg, 19.4 kg, and 33.0 kg, respectively, were observed. The differences observed in mean BMI and waist circumference were 4.9 kg/m(2) (P = 0.0004) and 21.7 cm (P = 0.003), respectively. CONCLUSIONS: ESG is effective in achieving weight loss with minimal adverse events. This approach may provide a cost-effective outpatient procedure to add to the steadily growing armamentarium available for treatment of this significant epidemic. © Georg Thieme Verlag KG Stuttgart · New York.
Entities: Disease
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Year: 2014
PMID： 25380510 DOI： 10.1055/s-0034-1390773
Source DB: PubMed Journal: Endoscopy ISSN： 0013-726X Impact factor: 10.093