| Literature DB >> 25378847 |
Pavan Tiwari1, Karan Madan1, Deepali Jain2, Rakesh Kumar3, Anant Mohan1, Randeep Guleria1.
Abstract
A young male patient had been evaluated for pleural effusion at another center wherein on the basis of exudative, lymphocyte predominant pleural effusion with high pleural fluid adenosine deaminase (ADA) levels and tuberculin skin test (TST) reactivity, antituberculous medications had been administered. Reevaluation in view of worsening symptoms led to confirmation of the diagnosis of T-cell lymphoblastic lymphoma with pleuro-peritoneal lymphomatosis and tonsillar involvement. This case highlights the fact that elevated ADA levels should not be taken as surrogate for a diagnosis of TB in the absence of histopathological/microbiological confirmation even in countries with high tuberculosis (TB) prevalence. Tonsil in an uncommon site of involvement in patients with T-cell lymphoma. As the diagnosis in our patient was confirmed from biopsy of a tonsillar mass, a thorough physical examination should be performed in all patients with a suspected diagnosis of lymphoma.Entities:
Keywords: Adenosine deaminase; T-cell lymphoma; non-Hodgkin's lymphoma; tuberculosis
Year: 2014 PMID: 25378847 PMCID: PMC4220321 DOI: 10.4103/0970-2113.142125
Source DB: PubMed Journal: Lung India ISSN: 0970-2113