Literature DB >> 25378847

Pleuro-peritoneal lymphomatosis with concurrent tonsillar involvement in T-cell nonHodgkin's lymphoma: Clinical presentation mimicking disseminated tuberculosis.

Pavan Tiwari1, Karan Madan1, Deepali Jain2, Rakesh Kumar3, Anant Mohan1, Randeep Guleria1.   

Abstract

A young male patient had been evaluated for pleural effusion at another center wherein on the basis of exudative, lymphocyte predominant pleural effusion with high pleural fluid adenosine deaminase (ADA) levels and tuberculin skin test (TST) reactivity, antituberculous medications had been administered. Reevaluation in view of worsening symptoms led to confirmation of the diagnosis of T-cell lymphoblastic lymphoma with pleuro-peritoneal lymphomatosis and tonsillar involvement. This case highlights the fact that elevated ADA levels should not be taken as surrogate for a diagnosis of TB in the absence of histopathological/microbiological confirmation even in countries with high tuberculosis (TB) prevalence. Tonsil in an uncommon site of involvement in patients with T-cell lymphoma. As the diagnosis in our patient was confirmed from biopsy of a tonsillar mass, a thorough physical examination should be performed in all patients with a suspected diagnosis of lymphoma.

Entities:  

Keywords:  Adenosine deaminase; T-cell lymphoma; non-Hodgkin's lymphoma; tuberculosis

Year:  2014        PMID: 25378847      PMCID: PMC4220321          DOI: 10.4103/0970-2113.142125

Source DB:  PubMed          Journal:  Lung India        ISSN: 0970-2113


  8 in total

1.  Intensive ALL-type therapy without local radiotherapy provides a 90% event-free survival for children with T-cell lymphoblastic lymphoma: a BFM group report.

Authors:  A Reiter; M Schrappe; W D Ludwig; M Tiemann; R Parwaresch; M Zimmermann; E Schirg; G Henze; G Schellong; H Gadner; H Riehm
Journal:  Blood       Date:  2000-01-15       Impact factor: 22.113

Review 2.  Lymphoblastic lymphoma.

Authors:  Sergio Cortelazzo; Maurilio Ponzoni; Andrés J M Ferreri; Dieter Hoelzer
Journal:  Crit Rev Oncol Hematol       Date:  2011-01-26       Impact factor: 6.312

3.  Distribution of various subtypes of non-Hodgkin's lymphoma in India: a study of 2773 lymphomas using R.E.A.L. and WHO Classifications.

Authors:  K N Naresh; V Srinivas; C S Soman
Journal:  Ann Oncol       Date:  2000       Impact factor: 32.976

4.  Outcome of adult patients with T-lymphoblastic lymphoma treated according to protocols for acute lymphoblastic leukemia.

Authors:  Dieter Hoelzer; Nicola Gökbuget; Werner Digel; Thomas Faak; Michael Kneba; Regina Reutzel; Joanna Romejko-Jarosinska; Jacek Zwolinski; Jan Walewski
Journal:  Blood       Date:  2002-06-15       Impact factor: 22.113

5.  Pleural tuberculosis following lung cancer chemotherapy: a report of two cases proven pathologically by pleural biopsy.

Authors:  Karan Madan; Navneet Singh; Ashim Das; Digambar Behera
Journal:  BMJ Case Rep       Date:  2013-01-22

6.  CT findings of lymphoma with peritoneal, omental and mesenteric involvement: peritoneal lymphomatosis.

Authors:  Devrim Karaosmanoglu; Musturay Karcaaltincaba; Berna Oguz; Deniz Akata; Mustafa Ozmen; Okan Akhan
Journal:  Eur J Radiol       Date:  2008-05-29       Impact factor: 3.528

7.  Adenosine deaminase and interferon gamma measurements for the diagnosis of tuberculous pleurisy: a meta-analysis.

Authors:  S Greco; E Girardi; R Masciangelo; G B Capoccetta; C Saltini
Journal:  Int J Tuberc Lung Dis       Date:  2003-08       Impact factor: 2.373

Review 8.  Diagnostic accuracy of adenosine deaminase in tuberculous pleurisy: a meta-analysis.

Authors:  Qiu-Li Liang; Huan-Zhong Shi; Ke Wang; Shou-Ming Qin; Xue-Jun Qin
Journal:  Respir Med       Date:  2008-01-28       Impact factor: 3.415

  8 in total

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