Literature DB >> 25376373

Hypoxia-induced p38 MAPK activation reduces Mcl-1 expression and facilitates sensitivity towards BH3 mimetics in chronic lymphocytic leukemia.

M F Huelsemann1, M Patz1, L Beckmann1, K Brinkmann2, T Otto3, J Fandrey3, H J Becker4, S Theurich4, M von Bergwelt-Baildon4, C P Pallasch1, R P Zahedi5, H Kashkar2, H C Reinhardt1, M Hallek1, C M Wendtner6, L P Frenzel1.   

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Year:  2014        PMID： 25376373     DOI： 10.1038/leu.2014.320

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  15 in total

1.  NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes.

Authors:  H H Lee; H Dadgostar; Q Cheng; J Shu; G Cheng
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

2.  Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.

Authors:  Marina Konopleva; Rooha Contractor; Twee Tsao; Ismael Samudio; Peter P Ruvolo; Shinichi Kitada; Xingming Deng; Dayong Zhai; Yue-Xi Shi; Thomas Sneed; Monique Verhaegen; Maria Soengas; Vivian R Ruvolo; Teresa McQueen; Wendy D Schober; Julie C Watt; Tilahun Jiffar; Xiaoyang Ling; Frank C Marini; David Harris; Martin Dietrich; Zeev Estrov; James McCubrey; W Stratford May; John C Reed; Michael Andreeff
Journal:  Cancer Cell       Date:  2006-11       Impact factor: 31.743

3.  Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease.

Authors:  Andrew W Roberts; John F Seymour; Jennifer R Brown; William G Wierda; Thomas J Kipps; Seong Lin Khaw; Dennis A Carney; Simon Z He; David C S Huang; Hao Xiong; Yue Cui; Todd A Busman; Evelyn M McKeegan; Andrew P Krivoshik; Sari H Enschede; Rod Humerickhouse
Journal:  J Clin Oncol       Date:  2011-12-19       Impact factor: 44.544

Review 4.  Targeting hypoxia in cancer therapy.

Authors:  William R Wilson; Michael P Hay
Journal:  Nat Rev Cancer       Date:  2011-06       Impact factor: 60.716

5.  Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells.

Authors:  P W Conrad; R T Rust; J Han; D E Millhorn; D Beitner-Johnson
Journal:  J Biol Chem       Date:  1999-08-13       Impact factor: 5.157

6.  Sorafenib-induced apoptosis of chronic lymphocytic leukemia cells is associated with downregulation of RAF and myeloid cell leukemia sequence 1 (Mcl-1).

Authors:  Jessie-F Fecteau; Ila S Bharati; Morgan O'Hayre; Tracy M Handel; Thomas J Kipps; Davorka Messmer
Journal:  Mol Med       Date:  2012-02-10       Impact factor: 6.354

7.  The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia.

Authors:  Yair Herishanu; Patricia Pérez-Galán; Delong Liu; Angélique Biancotto; Stefania Pittaluga; Berengere Vire; Federica Gibellini; Ndegwa Njuguna; Elinor Lee; Lawrence Stennett; Nalini Raghavachari; Poching Liu; J Philip McCoy; Mark Raffeld; Maryalice Stetler-Stevenson; Constance Yuan; Richard Sherry; Diane C Arthur; Irina Maric; Therese White; Gerald E Marti; Peter Munson; Wyndham H Wilson; Adrian Wiestner
Journal:  Blood       Date:  2010-10-12       Impact factor: 22.113

Review 8.  Microenvironmental interactions and survival of CLL B-cells.

Authors:  Irene Munk Pedersen; John Reed
Journal:  Leuk Lymphoma       Date:  2004-12

9.  Hypoxia causes the activation of nuclear factor kappa B through the phosphorylation of I kappa B alpha on tyrosine residues.

Authors:  A C Koong; E Y Chen; A J Giaccia
Journal:  Cancer Res       Date:  1994-03-15       Impact factor: 12.701

10.  Direct measurement of local oxygen concentration in the bone marrow of live animals.

Authors:  Joel A Spencer; Francesca Ferraro; Emmanuel Roussakis; Alyssa Klein; Juwell Wu; Judith M Runnels; Walid Zaher; Luke J Mortensen; Clemens Alt; Raphaël Turcotte; Rushdia Yusuf; Daniel Côté; Sergei A Vinogradov; David T Scadden; Charles P Lin
Journal:  Nature       Date:  2014-03-02       Impact factor: 49.962
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  14 in total

Review 1.  Pathways and mechanisms of venetoclax resistance.

Authors:  Prithviraj Bose; Varsha Gandhi; Marina Konopleva
Journal:  Leuk Lymphoma       Date:  2017-01-31

2.  Bcl-2 family member Mcl-1 expression is reduced under hypoxia by the E3 ligase FBW7 contributing to BNIP3 induced cell death in glioma cells.

Authors:  Yongqiang Chen; Elizabeth S Henson; Wenyan Xiao; Epsita Shome; Meghan B Azad; Teralee R Burton; Michelle Queau; Akshay Sathya; David D Eisenstat; Spencer B Gibson
Journal:  Cancer Biol Ther       Date:  2015-10-15       Impact factor: 4.742

Review 3.  The current state of the art of quantitative phosphoproteomics and its applications to diabetes research.

Authors:  Chi Yuet X'avia Chan; Marina A Gritsenko; Richard D Smith; Wei-Jun Qian
Journal:  Expert Rev Proteomics       Date:  2016       Impact factor: 3.940

4.  PIK-75 overcomes venetoclax resistance via blocking PI3K-AKT signaling and MCL-1 expression in mantle cell lymphoma.

Authors:  Shengjian Huang; Yang Liu; Zhihong Chen; Michael Wang; Vivian C Jiang
Journal:  Am J Cancer Res       Date:  2022-03-15       Impact factor: 6.166

5.  IBL-202 is synergistic with venetoclax in CLL under in vitro conditions that mimic the tumor microenvironment.

Authors:  Yandong Shen; Kyle Crassini; Narjis Fatima; Michael O'Dwyer; Michael O'Neill; Richard I Christopherson; Stephen P Mulligan; O Giles Best
Journal:  Blood Adv       Date:  2020-10-27

6.  An Antagomir to MicroRNA-106b-5p Ameliorates Cerebral Ischemia and Reperfusion Injury in Rats Via Inhibiting Apoptosis and Oxidative Stress.

Authors:  Pengfei Li; Meihong Shen; Feng Gao; Jinping Wu; Jiahui Zhang; Fengmeng Teng; Chunbing Zhang
Journal:  Mol Neurobiol       Date:  2016-03-29       Impact factor: 5.590

7.  Data-Driven Computational Modeling Identifies Determinants of Glioblastoma Response to SHP2 Inhibition.

Authors:  Evan K Day; Qing Zhong; Benjamin Purow; Matthew J Lazzara
Journal:  Cancer Res       Date:  2021-02-11       Impact factor: 13.312

8.  Inhibition of deubiquitinases primes glioblastoma cells to apoptosis in vitro and in vivo.

Authors:  Georg Karpel-Massler; Matei A Banu; Chang Shu; Marc-Eric Halatsch; Mike-Andrew Westhoff; Jeffrey N Bruce; Peter Canoll; Markus D Siegelin
Journal:  Oncotarget       Date:  2016-03-15

Review 9.  Current strategies and findings in clinically relevant post-translational modification-specific proteomics.

Authors:  Oliver Pagel; Stefan Loroch; Albert Sickmann; René P Zahedi
Journal:  Expert Rev Proteomics       Date:  2015-05-08       Impact factor: 3.940

10.  Pro-survival responses to the dual inhibition of anti-apoptotic Bcl-2 family proteins and mTOR-mediated signaling in hypoxic colorectal carcinoma cells.

Authors:  Karianne Risberg; Kathrine Røe Redalen; Linda Sønstevold; Tonje Bjørnetrø; Janne Sølvernes; Anne Hansen Ree
Journal:  BMC Cancer       Date:  2016-07-26       Impact factor: 4.430
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