Literature DB >> 25374087

[Detection of bilirubin, CCR1, troponin I and IL-6 in patients with acute myocardial infarction].

Bangguo Kang1, Yuzhong Mao1.   

Abstract

OBJECTIVE: To detect the levels of plasma C-C chemokine receptor type 1 (CCR1), serum total bilirubin (TBIL), troponin I and interleukin-6 (IL-6) in acute myocardial infarction (AMI) patients.
METHODS: AMI group and control group respectively contained 65 samples. Diazo was used to detect the levels of serum TBIL, direct bilirubin (DBIL) and indirect bilirubin (IBIL). ELISA was used to detect the level of CCR1. Troponin I and IL-6 were detected by chemiluminescence analysis and radioimmunoassay, respectively.
RESULTS: The levels of TBIL [(15.07±2.87) μmol/L] and IBIL [(9.32±4.58) μmol/L] were significantly lower in AMI group than in control group [TBIL (20.15±3.26) μmol/L, IBIL (14.48±3.90) μmol/L] (P<0.05). However, the levels of CCR1, troponin I and IL-6 [(3.76± 0.85) ng/mL, (15.88±2.43) U/mL, (207.60± 23.94) U/mL] in AMI group were significantly higher than those in control group [CCR1 (0.66±0.19) ng/mL, troponin I (0.33±0.07) U/mL, IL-6 (103.55±16.86) U/mL] (P<0.05).
CONCLUSION: The levels of CCR1, troponin I and IL-6 were increased and the level of serum bilirubin was decreased in AMI patients.

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Year:  2014        PMID: 25374087

Source DB:  PubMed          Journal:  Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi        ISSN: 1007-8738


  1 in total

1.  Genes associated with inflammation and the cell cycle may serve as biomarkers for the diagnosis and prognosis of acute myocardial infarction in a Chinese population.

Authors:  Jiang Su; Changqing Gao; Rong Wang; Cangsong Xiao; Ming Yang
Journal:  Mol Med Rep       Date:  2018-05-25       Impact factor: 2.952

  1 in total

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