Literature DB >> 25373771

Calluses flex their muscles to align bone fragments during fracture repair.

Jacqueline Nguyen1, Tamara Alliston2.   

Abstract

Neonatal animals spontaneously reduce fractures, yet the mechanical forces influencing this process are poorly understood. In this issue of Developmental Cell, Rot et al. (2014) show that muscle and the fracture callus actively position fractured neonatal bone fragments to restore their alignment, highlighting the multifaceted roles of mechanical cues in skeletal regeneration.

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Mesh:

Year:  2014        PMID: 25373771      PMCID: PMC4492116          DOI: 10.1016/j.devcel.2014.10.009

Source DB:  PubMed          Journal:  Dev Cell        ISSN: 1534-5807            Impact factor:   12.270


  9 in total

Review 1.  One load to rule them all: mechanical control of the musculoskeletal system in development and aging.

Authors:  Yulia Shwartz; Einat Blitz; Elazar Zelzer
Journal:  Differentiation       Date:  2013-08-14       Impact factor: 3.880

2.  Indian and sonic hedgehogs regulate synchondrosis growth plate and cranial base development and function.

Authors:  Blanche Young; Nancy Minugh-Purvis; Tsuyoshi Shimo; Benoit St-Jacques; Masahiro Iwamoto; Motomi Enomoto-Iwamoto; Eiki Koyama; Maurizio Pacifici
Journal:  Dev Biol       Date:  2006-07-29       Impact factor: 3.582

Review 3.  Mechanical loading history and skeletal biology.

Authors:  D R Carter
Journal:  J Biomech       Date:  1987       Impact factor: 2.712

4.  Magnitudes of local stress and strain along bony surfaces predict the course and type of fracture healing.

Authors:  L E Claes; C A Heigele
Journal:  J Biomech       Date:  1999-03       Impact factor: 2.712

5.  Path analysis of factors for delayed healing and nonunion in 416 operatively treated tibial shaft fractures.

Authors:  Laurent Audigé; Damian Griffin; Mohit Bhandari; James Kellam; Thomas P Rüedi
Journal:  Clin Orthop Relat Res       Date:  2005-09       Impact factor: 4.176

Review 6.  Fracture healing under healthy and inflammatory conditions.

Authors:  Lutz Claes; Stefan Recknagel; Anita Ignatius
Journal:  Nat Rev Rheumatol       Date:  2012-01-31       Impact factor: 20.543

7.  A mechanical Jack-like Mechanism drives spontaneous fracture healing in neonatal mice.

Authors:  Chagai Rot; Tomer Stern; Ronen Blecher; Ben Friesem; Elazar Zelzer
Journal:  Dev Cell       Date:  2014-10-27       Impact factor: 12.270

8.  Molecular aspects of healing in stabilized and non-stabilized fractures.

Authors:  A X Le; T Miclau; D Hu; J A Helms
Journal:  J Orthop Res       Date:  2001-01       Impact factor: 3.494

Review 9.  Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation.

Authors:  Louis C Gerstenfeld; Dennis M Cullinane; George L Barnes; Dana T Graves; Thomas A Einhorn
Journal:  J Cell Biochem       Date:  2003-04-01       Impact factor: 4.429

  9 in total

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