Literature DB >> 25373373

[Relationship between visceral fat and development of colorectal neoplasms using computed tomographic colonography and adipocytokine levels].

Yoshiki Kimura1, Hiroshi Matsumoto, Motoyasu Oosawa, Minoru Fujita, Ken-Ichi Tarumi, Tomoari Kamada, Akiko Shiotani, Ken Haruma.   

Abstract

We evaluated the relationship between colorectal neoplasms and visceral obesity using computed tomographic colonography and adipocytokine levels. We included 123 patients and classified them into four groups as per computed tomographic colonography: no lesion (NL; n=40), adenomatous polyp (polyp; n=41), early colorectal cancer (eCRC; n=21), and advanced CRC (aCRC; n=21). We also measured the patients' serum metabolic markers and adipocytokine levels. The visceral adiposity index in the polyp and eCRC groups was significantly higher than that in the NL group. Visceral obesity is an important risk factor for the development of colonic polyps. Computed tomographic colonography could be a useful examination technique not only for diagnosis of colorectal neoplasms but also for simultaneous evaluation of visceral obesity.

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Year:  2014        PMID: 25373373

Source DB:  PubMed          Journal:  Nihon Shokakibyo Gakkai Zasshi        ISSN: 0446-6586


  1 in total

Review 1.  Circulating levels of C-reactive protein, interleukin-6 and tumor necrosis factor-α and risk of colorectal adenomas: a meta-analysis.

Authors:  Xiaoqian Zhang; Shanglong Liu; Yanbing Zhou
Journal:  Oncotarget       Date:  2016-09-27
  1 in total

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