Literature DB >> 25372907

Addition of long-distance heart procurement promotes changes in heart transplant waiting list status.

Fernando Antibas Atik1, Carolina Fatima Couto1, Freddy Ponce Tirado1, Camila Scatolin Moraes1, Renato Bueno Chaves1, Nubia W Vieira1, João Gabbardo Reis1.   

Abstract

OBJECTIVE: Evaluate the addition of long-distance heart procurement on a heart transplant program and the status of heart transplant recipients waiting list.
METHODS: Between September 2006 and October 2012, 72 patients were listed as heart transplant recipients. Heart transplant was performed in 41 (57%), death on the waiting list occurred in 26 (36%) and heart recovery occurred in 5 (7%). Initially, all transplants were performed with local donors. Long-distance, interstate heart procurement initiated in February 2011. Thirty (73%) transplants were performed with local donors and 11 (27%) with long-distance donors (mean distance=792 km±397).
RESULTS: Patients submitted to interstate heart procurement had greater ischemic times (212 min ± 32 versus 90 min±18; P<0.0001). Primary graft dysfunction (distance 9.1% versus local 26.7%; P=0.23) and 1 month and 12 months actuarial survival (distance 90.1% and 90.1% versus local 90% and 86.2%; P=0.65 log rank) were similar among groups. There were marked incremental transplant center volume (64.4% versus 40.7%, P=0.05) with a tendency on less waiting list times (median 1.5 month versus 2.4 months, P=0.18). There was a tendency on reduced waiting list mortality (28.9% versus 48.2%, P=0.09).
CONCLUSION: Incorporation of long-distance heart procurement, despite being associated with longer ischemic times, does not increase morbidity and mortality rates after heart transplant. It enhances viable donor pool, and it may reduce waiting list recipient mortality as well as waiting time.

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Year:  2014        PMID: 25372907      PMCID: PMC4412323          DOI: 10.5935/1678-9741.20140046

Source DB:  PubMed          Journal:  Rev Bras Cir Cardiovasc


  11 in total

Review 1.  Current preservation technology and future prospects of thoracic organs. Part 2: heart.

Authors:  Steven Jacobs; Filip Rega; Bart Meyns
Journal:  Curr Opin Organ Transplant       Date:  2010-04       Impact factor: 2.640

2.  Does the cardioplegic solution have an effect on early outcomes following heart transplantation?

Authors:  Aldo Cannata; Luca Botta; Tiziano Colombo; Claudio F Russo; Corrado Taglieri; Giuseppe Bruschi; Bruno Merlanti; Maria Frigerio; Luigi Martinelli
Journal:  Eur J Cardiothorac Surg       Date:  2012-04       Impact factor: 4.191

3.  The Registry of the International Society for Heart and Lung Transplantation: 29th official adult heart transplant report--2012.

Authors:  Josef Stehlik; Leah B Edwards; Anna Y Kucheryavaya; Christian Benden; Jason D Christie; Anne I Dipchand; Fabienne Dobbels; Richard Kirk; Axel O Rahmel; Marshall I Hertz
Journal:  J Heart Lung Transplant       Date:  2012-10       Impact factor: 10.247

4.  Associated factors with survivals in patients undergoing orthotopic heart transplant using retrograde blood microcardioplegia.

Authors:  Carlos Fernando Ramos Lavagnoli; Elaine Soraya Barbosa de Oliveira Severino; Karlos Alexandre de Souza Vilarinho; Lindemberg da Mota Silveira Filho; Pedro Paulo Martins de Oliveira; Orlando Petrucci; Reinaldo Wilson Vieira; Domingo Marcolino Braile
Journal:  Rev Bras Cir Cardiovasc       Date:  2012 Jul-Sep

5.  Organ storage with University of Wisconsin solution is associated with improved outcomes after orthotopic heart transplantation.

Authors:  Timothy J George; George J Arnaoutakis; William A Baumgartner; Ashish S Shah; John V Conte
Journal:  J Heart Lung Transplant       Date:  2011-06-17       Impact factor: 10.247

6.  Successful long-term outcome with prolonged ischemic time cardiac allografts.

Authors:  E M Briganti; P J Bergin; F L Rosenfeldt; D S Esmore; M Rabinov
Journal:  J Heart Lung Transplant       Date:  1995 Sep-Oct       Impact factor: 10.247

7.  Extending cardiac allograft ischemic time and donor age: effect on survival and long-term cardiac function.

Authors:  P W Pflugfelder; N R Singh; F N McKenzie; A H Menkis; R J Novick; W J Kostuk
Journal:  J Heart Lung Transplant       Date:  1991 May-Jun       Impact factor: 10.247

8.  Duration of graft cold ischemia does not affect outcomes in pediatric heart transplant recipients.

Authors:  Albertus M Scheule; Grenith J Zimmerman; Joyce K Johnston; Anees J Razzouk; Steven R Gundry; Leonard L Bailey
Journal:  Circulation       Date:  2002-09-24       Impact factor: 29.690

9.  Prolonged preservation of human pediatric hearts for transplantation: correlation of ischemic time and subsequent function.

Authors:  M Kawauchi; S R Gundry; J A de Begona; D A Fullerton; A J Razzouk; M Boucek; M Kanakriyeh; L L Bailey
Journal:  J Heart Lung Transplant       Date:  1993 Jan-Feb       Impact factor: 10.247

10.  Oxidative stress implication after prolonged storage donor heart with blood versus crystalloid cardioplegia and reperfusion versus static storage.

Authors:  Jean-Christophe Charniot; Dominique Bonnefont-Rousselot; Jean-Paul Albertini; Sylvie Dever; Noelle Vignat; Patrick Nataf; Alain Pavie; Jean-Jacques Monsuez; Jacques DeLattre; Jean-Yves Artigou
Journal:  J Surg Res       Date:  2009-04-21       Impact factor: 2.192

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