Literature DB >> 2537134

The effect of gallium on seeded hydroxyapatite growth.

R Donnelly1, A Boskey.   

Abstract

Gallium chloride in solution at concentrations of 10-100 microM inhibits the seeded growth of hydroxyapatite from metastable calcium phosphate solutions. Using initial rate data, an effective rate constant for the process of crystal growth can be derived; this rate constant varies with gallium concentration in a log-dose/response fashion. The disappearance of gallium occurs disproportionately fast in the early stages of the experiments. This suggests that gallium acts by adsorbing to the crystal surface where it inhibits crystal growth.

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Year:  1989        PMID： 2537134     DOI： 10.1007/bf02556473

Source DB:  PubMed          Journal:  Calcif Tissue Int        ISSN： 0171-967X            Impact factor:   4.333


  14 in total

1.  The binding of pyrophosphate and two diphosphonates by hydroxyapatite crystals.

Authors:  A Jung; S Bisaz; H Fleisch
Journal:  Calcif Tissue Res       Date:  1973-03-30

2.  A new and convenient colorimetric determination of inorganic orthophosphate and its application to the assay of inorganic pyrophosphatase.

Authors:  J K Heinonen; R J Lahti
Journal:  Anal Biochem       Date:  1981-05-15       Impact factor: 3.365

3.  In vitro model of aluminum-induced osteomalacia: inhibition of hydroxyapatite formation and growth.

Authors:  N C Blumenthal; A S Posner
Journal:  Calcif Tissue Int       Date:  1984-07       Impact factor: 4.333

4.  Bone aluminum and histomorphometric features of renal osteodystrophy.

Authors:  A B Hodsman; D J Sherrard; A C Alfrey; S Ott; A S Brickman; N L Miller; N A Maloney; J W Coburn
Journal:  J Clin Endocrinol Metab       Date:  1982-03       Impact factor: 5.958

5.  The effect of aluminum on the rate of dissolution of calcium hydroxyapatite--a contribution to the understanding of aluminum-induced bone diseases.

Authors:  M R Christoffersen; J Christoffersen
Journal:  Calcif Tissue Int       Date:  1985-12       Impact factor: 4.333

6.  Gallium nitrate for acute treatment of cancer-related hypercalcemia: clinicopharmacological and dose response analysis.

Authors:  R P Warrell; A Skelos; N W Alcock; R S Bockman
Journal:  Cancer Res       Date:  1986-08       Impact factor: 12.701

7.  Trace metal-citric acid complexes as inhibitors of calcification and crystal growth. I. Effects of Fe(III), Cr(III) and Al(III) complexes on calcium phosphate crystal growth.

Authors:  J L Meyer; W C Thomas
Journal:  J Urol       Date:  1982-12       Impact factor: 7.450

8.  Gallium nitrate inhibits accelerated bone turnover in patients with bone metastases.

Authors:  R P Warrell; N W Alcock; R S Bockman
Journal:  J Clin Oncol       Date:  1987-02       Impact factor: 44.544

9.  Effect of gallium on bone mineral properties.

Authors:  M A Repo; R S Bockman; F Betts; A L Boskey; N W Alcock; R P Warrell
Journal:  Calcif Tissue Int       Date:  1988-11       Impact factor: 4.333

10.  The inhibitory effect of cartilage proteoglycans on hydroxyapatite growth.

Authors:  C C Chen; A L Boskey; L C Rosenberg
Journal:  Calcif Tissue Int       Date:  1984-05       Impact factor: 4.333
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  2 in total

Review 1.  Gallium nitrate. A review of its pharmacological properties and therapeutic potential in cancer related hypercalcaemia.

Authors:  P A Todd; A Fitton
Journal:  Drugs       Date:  1991-08       Impact factor: 9.546

2.  Exploring calcium oxalate crystallization: a constant composition approach.

Authors:  Ann M Kolbach-Mandel; Jack G Kleinman; Jeffrey A Wesson
Journal:  Urolithiasis       Date:  2015-05-28       Impact factor: 3.436
  2 in total

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