Literature DB >> 25371043

Vitamin D, vascular calcification and mortality among alcoholics.

Geraldine Quintero-Platt1, Emilio González-Reimers2, M Candelaria Martín-González1, Carlos Jorge-Ripper1, Rubén Hernández-Luis1, Pedro Abreu-González3, Melchor Rodríguez-Gaspar1, Francisco Santolaria-Fernández1.   

Abstract

AIMS: To analyze the relationship between low vitamin D levels and mortality among alcoholics.
METHODS: One hundred twenty-eight alcoholic patients admitted to our hospital were followed up as outpatients. Nutritional status was evaluated measuring percentages of fat and lean mass in different body compartments.
RESULTS: Lower vitamin D levels were observed in patients with worse liver function. Vitamin D was lower in patients with lower total lean mass (Z = 2.8, P = 0.005), but it was not related to fat mass. There was a significant trend to higher long-term mortality among non-cirrhotics with vitamin D levels below 30 ng/ml, although Cox's regression model revealed that only Child score and age were independently related to mortality.
CONCLUSION: Vitamin D deficiency is common among alcoholic patients and is associated with low lean mass and liver dysfunction. Among non-cirrhotics, serum vitamin D levels below 30 ng/ml are associated with a greater long-term mortality.
© The Author 2014. Medical Council on Alcohol and Oxford University Press. All rights reserved.

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Year:  2014        PMID: 25371043     DOI: 10.1093/alcalc/agu076

Source DB:  PubMed          Journal:  Alcohol Alcohol        ISSN: 0735-0414            Impact factor:   2.826


  2 in total

1.  Single and simultaneous effects of acrylamide and ethanol on bone microstructure of mice after one remodeling cycle.

Authors:  Anna Sarocka; Veronika Kovacova; Radoslav Omelka; Birgit Grosskopf; Edyta Kapusta; Zofia Goc; Grzegorz Formicki; Monika Martiniakova
Journal:  BMC Pharmacol Toxicol       Date:  2019-07-01       Impact factor: 2.483

2.  Golden opportunity for intervention? Identifying vitamin D deficiency in patients with substance use disorders in hospital.

Authors:  E Naomi Smith; Siobhan Gee; Gerri O'Brien; Pitchy-Ann Vicente; Rosemary Griffith; Rina Patel; Joshua Stapleton; Emily Finch; Naina Shah; Fiona Gaughran; David Taylor; John Strang; Nicola J Kalk
Journal:  BMJ Open Qual       Date:  2022-02
  2 in total

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