Literature DB >> 25368176

Simple battery armor to protect against gastrointestinal injury from accidental ingestion.

Bryan Laulicht1, Giovanni Traverso2, Vikram Deshpande3, Robert Langer4, Jeffrey M Karp5.   

Abstract

Inadvertent battery ingestion in children and the associated morbidity and mortality results in thousands of emergency room visits every year. Given the risk for serious electrochemical burns within hours of ingestion, the current standard of care for the treatment of batteries in the esophagus is emergent endoscopic removal. Safety standards now regulate locked battery compartments in toys, which have resulted in a modest reduction in inadvertent battery ingestion; specifically, 3,461 ingestions were reported in 2009, and 3,366 in 2013. Aside from legislation, minimal technological development has taken place at the level of the battery to limit injury. We have constructed a waterproof, pressure-sensitive coating, harnessing a commercially available quantum tunneling composite. Quantum tunneling composite coated (QTCC) batteries are nonconductive in the low-pressure gastrointestinal environment yet conduct within the higher pressure of standard battery housings. Importantly, this coating technology enables most battery-operated equipment to be powered without modification. If these new batteries are swallowed, they limit the external electrolytic currents responsible for tissue injury. We demonstrate in a large-animal model a significant decrease in tissue injury with QTCC batteries compared with uncoated control batteries. In summary, here we describe a facile approach to increasing the safety of batteries by minimizing the risk for electrochemical burn if the batteries are inadvertently ingested, without the need for modification of most battery-powered devices.

Entities:  

Keywords:  battery-induced injury; button battery safety; coin cell battery ingestion; esophageal injury; ingestion of foreign bodies

Mesh:

Substances:

Year:  2014        PMID: 25368176      PMCID: PMC4246317          DOI: 10.1073/pnas.1418423111

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  12 in total

1.  Corrosive esophageal injury by button battery.

Authors:  Andrew J Walker; Freddy Caldera
Journal:  Gastrointest Endosc       Date:  2013-06-22       Impact factor: 9.427

2.  Management of ingested foreign bodies and food impactions.

Authors:  Steven O Ikenberry; Terry L Jue; Michelle A Anderson; Vasundhara Appalaneni; Subhas Banerjee; Tamir Ben-Menachem; G Anton Decker; Robert D Fanelli; Laurel R Fisher; Norio Fukami; M Edwyn Harrison; Rajeev Jain; Khalid M Khan; Mary Lee Krinsky; John T Maple; Ravi Sharaf; Laura Strohmeyer; Jason A Dominitz
Journal:  Gastrointest Endosc       Date:  2011-06       Impact factor: 9.427

3.  Injuries from batteries among children aged <13 years--United States, 1995-2010.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2012-08-31       Impact factor: 17.586

4.  Esophageal manometry in 95 healthy adult volunteers. Variability of pressures with age and frequency of "abnormal" contractions.

Authors:  J E Richter; W C Wu; D N Johns; J N Blackwell; J L Nelson; J A Castell; D O Castell
Journal:  Dig Dis Sci       Date:  1987-06       Impact factor: 3.199

Review 5.  Button battery ingestions. A review of 56 cases.

Authors:  T L Litovitz
Journal:  JAMA       Date:  1983-05-13       Impact factor: 56.272

6.  20 mm lithium button battery causing an oesophageal perforation in a toddler: lessons in diagnosis and treatment.

Authors:  Giampiero Soccorso; Ole Grossman; Massimo Martinelli; Sean S Marven; Kirtik Patel; Mike Thomson; Julian P Roberts
Journal:  Arch Dis Child       Date:  2012-05-01       Impact factor: 3.791

7.  Experimental investigation of battery-induced esophageal burn injury in rabbits.

Authors:  T Yoshikawa; S Asai; Y Takekawa; A Kida; K Ishikawa
Journal:  Crit Care Med       Date:  1997-12       Impact factor: 7.598

8.  A review of esophageal disc battery ingestions and a protocol for management.

Authors:  Stanley J Kimball; Albert H Park; Michael D Rollins; Johannes Fredrik Grimmer; Harlan Muntz
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2010-09

9.  An unusual case of button battery-induced traumatic tracheoesophageal fistula.

Authors:  Nicholas B Slamon; James H Hertzog; Scott H Penfil; Russell C Raphaely; Christian Pizarro; Christopher D Derby
Journal:  Pediatr Emerg Care       Date:  2008-05       Impact factor: 1.454

10.  Severe injuries from coin cell battery ingestions: 2 case reports.

Authors:  Joshua M Hamilton; Scott A Schraff; David M Notrica
Journal:  J Pediatr Surg       Date:  2009-03       Impact factor: 2.545

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  9 in total

Review 1.  Button battery ingestion in children-a potentially catastrophic event of which all radiologists must be aware.

Authors:  Thomas Semple; Alistair D Calder; Madhavan Ramaswamy; Kieran McHugh
Journal:  Br J Radiol       Date:  2017-10-26       Impact factor: 3.039

Review 2.  Button Battery Ingestion in Children: A Paradigm for Management of Severe Pediatric Foreign Body Ingestions.

Authors:  Kristina Leinwand; David E Brumbaugh; Robert E Kramer
Journal:  Gastrointest Endosc Clin N Am       Date:  2016-01

3.  A case of battery ingestion in a pediatric patient: what is its importance?

Authors:  Elie Alam; Marc Mourad; Samir Akel; Usamah Hadi
Journal:  Case Rep Pediatr       Date:  2015-01-27

4.  Prolonged energy harvesting for ingestible devices.

Authors:  Phillip Nadeau; Dina El-Damak; Dean Glettig; Yong Lin Kong; Stacy Mo; Cody Cleveland; Lucas Booth; Niclas Roxhed; Robert Langer; Anantha P Chandrakasan; Giovanni Traverso
Journal:  Nat Biomed Eng       Date:  2017-02-06       Impact factor: 25.671

5.  Wireless Power Transfer to Millimeter-Sized Gastrointestinal Electronics Validated in a Swine Model.

Authors:  Abubakar Abid; Jonathan M O'Brien; Taylor Bensel; Cody Cleveland; Lucas Booth; Brian R Smith; Robert Langer; Giovanni Traverso
Journal:  Sci Rep       Date:  2017-04-27       Impact factor: 4.379

6.  Battery Ingestion with Colonic Perforation after Colostomy Closure in a Toddler.

Authors:  Annamarie C Lukish; Vivien Pat; Anisha Apte; Marc A Levitt
Journal:  European J Pediatr Surg Rep       Date:  2022-03-10

7.  Vocal cord paralysis following lithium button battery ingestion in children.

Authors:  Qingchuan Duan; Fengzhen Zhang; Guixiang Wang; Hua Wang; Hongbin Li; Jing Zhao; Jie Zhang; Xin Ni
Journal:  Eur J Pediatr       Date:  2020-10-13       Impact factor: 3.183

Review 8.  Current management of button battery injuries.

Authors:  Rishabh Sethia; Hannah Gibbs; Ian N Jacobs; James S Reilly; Keith Rhoades; Kris R Jatana
Journal:  Laryngoscope Investig Otolaryngol       Date:  2021-04-15

9.  3D-Printed Gastric Resident Electronics.

Authors:  Yong Lin Kong; Xingyu Zou; Caitlin A McCandler; Ameya R Kirtane; Shen Ning; Jianlin Zhou; Abubakar Abid; Mousa Jafari; Jaimie Rogner; Daniel Minahan; Joy E Collins; Shane McDonnell; Cody Cleveland; Taylor Bensel; Siid Tamang; Graham Arrick; Alla Gimbel; Tiffany Hua; Udayan Ghosh; Vance Soares; Nancy Wang; Aniket Wahane; Alison Hayward; Shiyi Zhang; Brian R Smith; Robert Langer; Giovanni Traverso
Journal:  Adv Mater Technol       Date:  2018-12-13
  9 in total

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