Literature DB >> 25367725

Dementia in older people: an update.

D LoGiudice1, R Watson.   

Abstract

Dementia is a common condition of the elderly characterised by multiple cognitive deficits resulting in a decline from previous level of function. In the older person, multiple pathologies contribute, including changes commonly seen in Alzheimer disease, dementia with Lewy bodies in addition to vascular changes. Comorbid factors, such as depression, delirium and polypharmacy can contribute to cognitive decline. Novel biomarkers and neuroimaging techniques may assist in the near future to improve accuracy of diagnosis. To date, pharmacological therapies have been largely unsuccessful and provide symptomatic relief only. The timely diagnosis of dementia can facilitate important discussions regarding personal and financial planning and introduce education and supports to the person with dementia and their carers. The person with dementia commonly experiences behavioural and psychological symptoms of dementia that may cause much distress, including to families and carers. Clinical guidelines indicate non-pharmacological approaches as first line measures, including attention to pain, nutrition and the environment. Dementia is recognised as a National Health Priority in Australia, and efforts to target risk factors as preventative measures to delay onset of dementia require further urgent consideration.
© 2014 The Authors; Internal Medicine Journal © 2014 Royal Australasian College of Physicians.

Entities:  

Keywords:  Alzheimer disease; dementia; neuroimaging; older people; risk factor

Mesh:

Year:  2014        PMID: 25367725     DOI: 10.1111/imj.12572

Source DB:  PubMed          Journal:  Intern Med J        ISSN: 1444-0903            Impact factor:   2.048


  10 in total

Review 1.  Experiences and practices of caregiving for older persons living with dementia in African countries: A qualitative scoping review.

Authors:  Isaac A Adedeji; Adesola Ogunniyi; David C Henderson; Nadia A Sam-Agudu
Journal:  Dementia (London)       Date:  2022-01-03

2.  The relationship between in-hospital location and outcomes of care in patients diagnosed with dementia and/or delirium diagnoses: analysis of patient journey.

Authors:  Lua Perimal-Lewis; Clare Bradley; Paul H Hakendorf; Craig Whitehead; Louise Heuzenroeder; Maria Crotty
Journal:  BMC Geriatr       Date:  2016-11-24       Impact factor: 3.921

3.  The Association between Polypharmacy and Dementia: A Nested Case-Control Study Based on a 12-Year Longitudinal Cohort Database in South Korea.

Authors:  Hae-Young Park; Ji-Won Park; Hong Ji Song; Hyun Soon Sohn; Jin-Won Kwon
Journal:  PLoS One       Date:  2017-01-05       Impact factor: 3.240

4.  Neuropsychiatric symptoms and executive function impairments in Alzheimer's disease and vascular dementia: The role of subcortical circuits.

Authors:  Chan Tiel; Felipe Kenji Sudo; Ana Beatriz Calmon
Journal:  Dement Neuropsychol       Date:  2019 Jul-Sep

5.  Dementia screening of geriatric patients by implementing an informant-based Alzheimer's disease eight-item tool in KSA.

Authors:  Amal A Ismail; Nada S Alghasham; Rawan E Alsukhaiber; Fatimah M Alnowiasser
Journal:  J Taibah Univ Med Sci       Date:  2020-11-30

6.  The efficacy of exergaming in people with major neurocognitive disorder residing in long-term care facilities: a pilot randomized controlled trial.

Authors:  Nathalie Swinnen; Mathieu Vandenbulcke; Eling D de Bruin; Riekje Akkerman; Brendon Stubbs; Joseph Firth; Davy Vancampfort
Journal:  Alzheimers Res Ther       Date:  2021-03-30       Impact factor: 6.982

7.  Increased Risk of Dementia in Patients With Acute Organophosphate and Carbamate Poisoning: A Nationwide Population-Based Cohort Study.

Authors:  Jiun-Nong Lin; Cheng-Li Lin; Ming-Chia Lin; Chung-Hsu Lai; Hsi-Hsun Lin; Chih-Hui Yang; Chia-Hung Kao
Journal:  Medicine (Baltimore)       Date:  2015-07       Impact factor: 1.817

Review 8.  Healthy Aging and Dementia: Two Roads Diverging in Midlife?

Authors:  Katie Irwin; Claire Sexton; Tarun Daniel; Brian Lawlor; Lorina Naci
Journal:  Front Aging Neurosci       Date:  2018-09-19       Impact factor: 5.750

9.  Relationship between Surgery under General Anesthesia and the Development of Dementia: A Systematic Review and Meta-Analysis.

Authors:  Je Jin Lee; Geun Joo Choi; Hyun Kang; Chong Wha Baek; Yong Hun Jung; Hwa Yong Shin; Yong Hee Park; Young Cheol Woo
Journal:  Biomed Res Int       Date:  2020-04-02       Impact factor: 3.411

10.  Cumulative use of therapeutic bladder anticholinergics and the risk of dementia in patients with lower urinary tract symptoms: a nationwide 12-year cohort study.

Authors:  Yi-Chi Wang; Yung-Liang Chen; Chun-Che Huang; Chung-Han Ho; Yu-Tung Huang; Ming-Ping Wu; Ming-Jung Ou; Chiu-Hsien Yang; Ping-Jen Chen
Journal:  BMC Geriatr       Date:  2019-12-30       Impact factor: 3.921

  10 in total

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