Literature DB >> 25365983

Long-term skin regeneration from a gene-targeted human epidermal stem cell clone.

Blanca Duarte1, Francesca Miselli2, Rodolfo Murillas1, Luis Espinosa-Hevia3, Juan Cruz Cigudosa3, Alessandra Recchia2, Marcela Del Río4, Fernando Larcher5.   

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Year:  2014        PMID： 25365983      PMCID： PMC4429743          DOI： 10.1038/mt.2014.187

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


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  13 in total

1.  Ex-vivo gene therapy restores LEKTI activity and corrects the architecture of Netherton syndrome-derived skin grafts.

Authors:  Wei-Li Di; Fernado Larcher; Ekaterina Semenova; Gill E Talbot; John I Harper; Marcela Del Rio; Adrian J Thrasher; Waseem Qasim
Journal:  Mol Ther       Date:  2010-09-28       Impact factor: 11.454

2.  Rare heritable skin diseases: targets for regenerative medicine.

Authors:  Jouni Uitto
Journal:  J Invest Dermatol       Date:  2012-11       Impact factor: 8.551

3.  TALEN-based gene correction for epidermolysis bullosa.

Authors:  Mark J Osborn; Colby G Starker; Amber N McElroy; Beau R Webber; Megan J Riddle; Lily Xia; Anthony P DeFeo; Richard Gabriel; Manfred Schmidt; Christof von Kalle; Daniel F Carlson; Morgan L Maeder; J Keith Joung; John E Wagner; Daniel F Voytas; Bruce R Blazar; Jakub Tolar
Journal:  Mol Ther       Date:  2013-04-02       Impact factor: 11.454

4.  In vivo assessment of acute UVB responses in normal and Xeroderma Pigmentosum (XP-C) skin-humanized mouse models.

Authors:  Marta García; Sara Llames; Eva García; Alvaro Meana; Natividad Cuadrado; Mar Recasens; Susana Puig; Eduardo Nagore; Nuria Illera; José Luis Jorcano; Marcela Del Rio; Fernando Larcher
Journal:  Am J Pathol       Date:  2010-06-17       Impact factor: 4.307

5.  Long-term engraftment of single genetically modified human epidermal holoclones enables safety pre-assessment of cutaneous gene therapy.

Authors:  Fernando Larcher; Elena Dellambra; Laura Rico; Sergio Bondanza; Rodolfo Murillas; Claudia Cattoglio; Fulvio Mavilio; José L Jorcano; Giovanna Zambruno; Marcela Del Rio
Journal:  Mol Ther       Date:  2007-06-19       Impact factor: 11.454

6.  ROCK inhibitor Y-27632 increases the cloning efficiency of limbal stem/progenitor cells by improving their adherence and ROS-scavenging capacity.

Authors:  Qingjun Zhou; Haoyun Duan; Yao Wang; Mingli Qu; Lingling Yang; Lixin Xie
Journal:  Tissue Eng Part C Methods       Date:  2012-12-28       Impact factor: 3.056

7.  Three clonal types of keratinocyte with different capacities for multiplication.

Authors:  Y Barrandon; H Green
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

8.  Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells.

Authors:  Fulvio Mavilio; Graziella Pellegrini; Stefano Ferrari; Francesca Di Nunzio; Enzo Di Iorio; Alessandra Recchia; Giulietta Maruggi; Giuliana Ferrari; Elena Provasi; Chiara Bonini; Sergio Capurro; Andrea Conti; Cristina Magnoni; Alberto Giannetti; Michele De Luca
Journal:  Nat Med       Date:  2006-11-19       Impact factor: 53.440

9.  Somatic correction of junctional epidermolysis bullosa by a highly recombinogenic AAV variant.

Authors:  Sandra P Melo; Leszek Lisowski; Elizaveta Bashkirova; Hanson H Zhen; Kirk Chu; Douglas R Keene; M Peter Marinkovich; Mark A Kay; Anthony E Oro
Journal:  Mol Ther       Date:  2014-01-06       Impact factor: 11.454

10.  Clonal analysis of stably transduced human epidermal stem cells in culture.

Authors:  M B Mathor; G Ferrari; E Dellambra; M Cilli; F Mavilio; R Cancedda; M De Luca
Journal:  Proc Natl Acad Sci U S A       Date:  1996-09-17       Impact factor: 11.205
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  7 in total

1.  Correction of recessive dystrophic epidermolysis bullosa by homology-directed repair-mediated genome editing.

Authors:  Jose Bonafont; Angeles Mencía; Esteban Chacón-Solano; Wai Srifa; Sriram Vaidyanathan; Rosa Romano; Marta Garcia; Rosario Hervás-Salcedo; Laura Ugalde; Blanca Duarte; Matthew H Porteus; Marcela Del Rio; Fernando Larcher; Rodolfo Murillas
Journal:  Mol Ther       Date:  2021-02-18       Impact factor: 12.910

2.  Deletion of a Pathogenic Mutation-Containing Exon of COL7A1 Allows Clonal Gene Editing Correction of RDEB Patient Epidermal Stem Cells.

Authors:  Ángeles Mencía; Cristina Chamorro; Jose Bonafont; Blanca Duarte; Almudena Holguin; Nuria Illera; Sara G Llames; Maria José Escámez; Ingrid Hausser; Marcela Del Río; Fernando Larcher; Rodolfo Murillas
Journal:  Mol Ther Nucleic Acids       Date:  2018-01-31       Impact factor: 8.886

3.  Clinically Relevant Correction of Recessive Dystrophic Epidermolysis Bullosa by Dual sgRNA CRISPR/Cas9-Mediated Gene Editing.

Authors:  Jose Bonafont; Ángeles Mencía; Marta García; Raúl Torres; Sandra Rodríguez; Marta Carretero; Esteban Chacón-Solano; Silvia Modamio-Høybjør; Lucía Marinas; Carlos León; María J Escamez; Ingrid Hausser; Marcela Del Río; Rodolfo Murillas; Fernando Larcher
Journal:  Mol Ther       Date:  2019-03-15       Impact factor: 11.454

Review 4.  Progress toward Treatment and Cure of Epidermolysis Bullosa: Summary of the DEBRA International Research Symposium EB2015.

Authors:  Jouni Uitto; Leena Bruckner-Tuderman; Angela M Christiano; John A McGrath; Cristina Has; Andrew P South; Brett Kopelan; E Clare Robinson
Journal:  J Invest Dermatol       Date:  2016-02       Impact factor: 8.551

5.  FOXM1 allows human keratinocytes to bypass the oncogene-induced differentiation checkpoint in response to gain of MYC or loss of p53.

Authors:  R Molinuevo; A Freije; I de Pedro; S W Stoll; J T Elder; A Gandarillas
Journal:  Oncogene       Date:  2016-07-25       Impact factor: 9.867

6.  Cut and Paste: Efficient Homology-Directed Repair of a Dominant Negative KRT14 Mutation via CRISPR/Cas9 Nickases.

Authors:  Thomas Kocher; Patricia Peking; Alfred Klausegger; Eva Maria Murauer; Josefina Piñón Hofbauer; Verena Wally; Thomas Lettner; Stefan Hainzl; Michael Ablinger; Johann Wolfgang Bauer; Julia Reichelt; Ulrich Koller
Journal:  Mol Ther       Date:  2017-08-24       Impact factor: 11.454

7.  Gene Editing for the Efficient Correction of a Recurrent COL7A1 Mutation in Recessive Dystrophic Epidermolysis Bullosa Keratinocytes.

Authors:  Cristina Chamorro; Angeles Mencía; David Almarza; Blanca Duarte; Hildegard Büning; Jessica Sallach; Ingrid Hausser; Marcela Del Río; Fernando Larcher; Rodolfo Murillas
Journal:  Mol Ther Nucleic Acids       Date:  2016-04-05       Impact factor: 10.183
  7 in total

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