Literature DB >> 25365621

Massive hemoptysis: a rare presentation of posterior mediastinal, giant, benign vagal schwannoma.

Anirban Das1, Sabyasachi Choudhury2, Sumitra Basuthakur2, Anghsuman Mukhopadhyay2, Siddhartha Mukherjee3.   

Abstract

Schwannomas are rare neurogenic tumor originating from Schwann cells of the nerve sheath, most frequently encountered type of posterior mediastinal tumors. In most cases, schwannomas are benign, malignant and multiple schwannomas are rare. Histopathologically, the tumor is composed of fascicles of spindle cells, which are strongly positive for S-100 proteins. Surgical resection is a treatment of choice, and prognosis is excellent. Here, we report a case of posterior mediastinal schwannoma in a 20- years old male patient who complained of right-sided back pain and two episodes of massive hemoptysis of recent onset. Contrast enhanced computed tomography (CECT) and magnetic resonance imaging of the chest showed a well circumscribed, heterogeneous mass in the posterior mediastinum, compressing the right lower lobe with widening of intervertebral foramens. CT-guided trucut biopsy revealed spindle cell neoplasm. On immunohistochemistry, tumor cells expressed strong positivity for S-100 protein. Final diagnosis was schwannoma, probably originating from the right vagus nerve. Surgical resection of the encapsulated tumor resulted in the successful recovery, without any recurrence over next one year follow up.

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Year:  2014        PMID: 25365621     DOI: 0141711/AIM.0013

Source DB:  PubMed          Journal:  Arch Iran Med        ISSN: 1029-2977            Impact factor:   1.354


  4 in total

1.  Surgical treatment of giant mediastinal tumors.

Authors:  Yu Fang; Zhiming Qin
Journal:  Turk Gogus Kalp Damar Cerrahisi Derg       Date:  2021-01-13       Impact factor: 0.332

2.  Endobronchial ultrasound-guided transbronchial needle aspiration as a diagnostic modality for schwannoma: A case report.

Authors:  Wei Liu; Yun Li; Lingjia Chen; Zhiguang Liu; Weidong Zhang
Journal:  Medicine (Baltimore)       Date:  2022-07-22       Impact factor: 1.817

Review 3.  Mediastinal tumors of peripheral nerve origin (so-called neurogenic tumors).

Authors:  Alberto M Marchevsky; Bonnie Balzer
Journal:  Mediastinum       Date:  2020-12-30

4.  Large mediastinal schwannoma with great vessel encroachment requiring vascular reconstruction: a case report.

Authors:  Joanne B Szewczyk; Krista Hachey; Jorge Rey; Dao M Nguyen; Nestor R Villamizar
Journal:  Mediastinum       Date:  2021-12-25
  4 in total

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