Literature DB >> 25364537

Right ventricle inflow obstructing mass proven to be a synovial sarcoma.

Guang-Won Seo1, Sang-Hoon Seol1, Pil-Sang Song1, Dong-Kie Kim1, Ki-Hun Kim1, Woo Gyeong Kim1, Yeon Mee Kim1, Sun Ju Oh1, Hee-Jae Jun1, Doo-Il Kim1.   

Abstract

Soft tissue sarcoma is the most common malignant cardiac tumor. The chief modes of presentation are embolization, obstruction, and arrhythmogenesis. We describe an unusual case of a 27-year-old man who presented with nausea and dyspnea on exertion. Transthoracic echocardiography and computed tomography revealed a huge mass in the right heart that extended through the inferior vena cava and right renal vein to the right kidney. The cardiac mass was resected, and an immunohistochemical analysis revealed it to be a TLE1-positive synovial sarcoma. After surgery, the patient received serial adjuvant chemotherapy. We herein describe the case with a brief review.

Entities:  

Keywords:  Cardiac tumor; SYT-SSX; TLE1; cardiac mass; synovial sarcoma (SS)

Year:  2014        PMID: 25364537      PMCID: PMC4215151          DOI: 10.3978/j.issn.2072-1439.2014.09.21

Source DB:  PubMed          Journal:  J Thorac Dis        ISSN: 2072-1439            Impact factor:   2.895


  12 in total

Review 1.  Cardiac tumours: diagnosis and management.

Authors:  L M Shapiro
Journal:  Heart       Date:  2001-02       Impact factor: 5.994

Review 2.  Updates on the cytogenetics and molecular genetics of bone and soft tissue tumors. Synovial sarcoma.

Authors:  Avery A Sandberg; Julia A Bridge
Journal:  Cancer Genet Cytogenet       Date:  2002-02

3.  Left atrial sarcoma mimicking obstructive pulmonary disease.

Authors:  Chau-Chyun Sheu; Sheng-Fung Lin; Chaw-Chi Chiu; Chee-Siong Lee; Chee-Yin Chai; Yi-Chang Liu; Ming-Shyan Huang
Journal:  J Clin Oncol       Date:  2007-04-01       Impact factor: 44.544

4.  TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies.

Authors:  Jefferson Terry; Tsuyoshi Saito; Subbaya Subramanian; Cindy Ruttan; Cristina R Antonescu; John R Goldblum; Erinn Downs-Kelly; Christopher L Corless; Brian P Rubin; Matt van de Rijn; Marc Ladanyi; Torsten O Nielsen
Journal:  Am J Surg Pathol       Date:  2007-02       Impact factor: 6.394

5.  Synovial sarcoma of the heart.

Authors:  Sajjad Hussain; Asif Ali Khan; Qaiser Khan
Journal:  J Coll Physicians Surg Pak       Date:  2012-11       Impact factor: 0.711

Review 6.  Primary cardiac synovial sarcoma.

Authors:  Ji-Gang Wang; Ning-Ning Li
Journal:  Ann Thorac Surg       Date:  2013-05-03       Impact factor: 4.330

Review 7.  Primary cardiac synovial sarcoma.

Authors:  Tanya Varma; Patrick Adegboyega
Journal:  Arch Pathol Lab Med       Date:  2012-04       Impact factor: 5.534

8.  Primary synovial sarcoma of the parietal pleura: a case report.

Authors:  Min-Kyun Kang; Kwang-Hyun Cho; Yang-Haeng Lee; Il-Yong Han; Young Chul Yoon; Kyung-Taek Park; Do Kyun Kang; Bo-Mi Kim
Journal:  Korean J Thorac Cardiovasc Surg       Date:  2013-04-09

9.  Primary cardiac pleomorphic sarcoma presenting as back pain in an 18-year-old man.

Authors:  Osama Alsara; Supratik Rayamajhi; Firas Ghanem; Elias Skaf; George S Abela
Journal:  Tex Heart Inst J       Date:  2013

10.  Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins.

Authors:  S Stifani; C M Blaumueller; N J Redhead; R E Hill; S Artavanis-Tsakonas
Journal:  Nat Genet       Date:  1992-10       Impact factor: 38.330

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