Literature DB >> 25364535

The challenging management of lung choriocarcinoma.

Lasha Gvinianidze1, Nikolaos Panagiotopoulos1, Wen Ling Woo1, Elaine Borg1, David Lawrence1.   

Abstract

The purpose of this paper is to highlight the existence and the management of lung choriocarcinoma (CCA), a rare category of lung tumors. We present a 42-year-old female that presented to our department with a PET positive lesion in the left upper lobe and a history of pregnancy 6 months prior to onset of symptoms. CT guided biopsy was inconclusive for diagnosis and the patient underwent a left thoracotomy and lingula sparing upper lobectomy. Histology revealed CCA of the lung and subsequently blood results confirmed the elevated b-HCG. CCA of the lung is a clinical entity that should be considered in the differential diagnosis of lung lesions in women after pregnancy.

Entities:  

Keywords:  Choriocarcinoma (CCA); lung metastases; pregnancy

Year:  2014        PMID: 25364535      PMCID: PMC4215135          DOI: 10.3978/j.issn.2072-1439.2014.09.18

Source DB:  PubMed          Journal:  J Thorac Dis        ISSN: 2072-1439            Impact factor:   2.895


  6 in total

1.  Current FIGO staging for cancer of the vagina, fallopian tube, ovary, and gestational trophoblastic neoplasia.

Authors: 
Journal:  Int J Gynaecol Obstet       Date:  2009-04       Impact factor: 3.561

2.  Management of metastatic high-risk gestational trophoblastic neoplasia: FIGO stages II-IV: risk factor score > or = 7.

Authors:  John R Lurain; Diljeet K Singh; Julian C Schink
Journal:  J Reprod Med       Date:  2010 May-Jun       Impact factor: 0.142

3.  Trophoblastic disease.

Authors:  Hextan Y S Ngan; Ernest I Kohorn; Laurence A Cole; Robert J Kurman; Seung J Kim; John R Lurain; Michael J Seckl; Shigeru Sasaki; John T Soper
Journal:  Int J Gynaecol Obstet       Date:  2012-10       Impact factor: 3.561

4.  EMA/CO for high-risk gestational trophoblastic tumors: results from a cohort of 272 patients.

Authors:  M Bower; E S Newlands; L Holden; D Short; C Brock; G J Rustin; R H Begent; K D Bagshawe
Journal:  J Clin Oncol       Date:  1997-07       Impact factor: 44.544

Review 5.  Combination chemotherapy for high-risk gestational trophoblastic tumour.

Authors:  Linyu Deng; Xue Yan; Jing Zhang; Taixiang Wu
Journal:  Cochrane Database Syst Rev       Date:  2009-04-15

Review 6.  Epidemiology and aetiology of gestational trophoblastic diseases.

Authors:  Andrea Altieri; Silvia Franceschi; Jacques Ferlay; Jennifer Smith; Carlo La Vecchia
Journal:  Lancet Oncol       Date:  2003-11       Impact factor: 41.316

  6 in total

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