To-Jung Tseng1, Tin-Hsin Hsiao2, Sung-Tsang Hsieh3, Yu-Lin Hsieh2. 1. Department of Anatomy, Faculty of Medicine, Chung Shan Medical University, Taichung, Taiwan. 2. Department of Anatomy, College of Medicine, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung, 80708, Taiwan. 3. Department of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Abstract
INTRODUCTION: The aims of this study were to determine the influences of: (1) timing of nerve decompression; and (2) nerve fiber types on the patterns of nerve conduction studies (NCS) after nerve injury. METHODS: Nerve conduction studies (NCS) were performed on 3 models of nerve injury: (1) crush injury due to transient nerve compression (crush group); (2) chronic constriction injury (CCI), or permanent compression (CCI group); and (3) CCI with removal of ligatures, or delayed nerve decompression (De-CCI group). RESULTS: There were distinct patterns of NCS recovery. The crush and De-CCI groups achieved similar motor nerve recovery, better than that of the CCI group. In contrast, recovery of sensory nerves was limited in the CCI and De-CCI groups and was lower than in the crush group. CONCLUSIONS: Immediate relief of compression resulted in the best recovery of motor and sensory nerve conduction. In contrast, delayed decompression restored only motor nerve conduction.
INTRODUCTION: The aims of this study were to determine the influences of: (1) timing of nerve decompression; and (2) nerve fiber types on the patterns of nerve conduction studies (NCS) after nerve injury. METHODS: Nerve conduction studies (NCS) were performed on 3 models of nerve injury: (1) crush injury due to transient nerve compression (crush group); (2) chronic constriction injury (CCI), or permanent compression (CCI group); and (3) CCI with removal of ligatures, or delayed nerve decompression (De-CCI group). RESULTS: There were distinct patterns of NCS recovery. The crush and De-CCI groups achieved similar motor nerve recovery, better than that of the CCI group. In contrast, recovery of sensory nerves was limited in the CCI and De-CCI groups and was lower than in the crush group. CONCLUSIONS: Immediate relief of compression resulted in the best recovery of motor and sensory nerve conduction. In contrast, delayed decompression restored only motor nerve conduction.
Authors: Natalia E Krzesniak; Anna Sarnowska; Anna Figiel-Dabrowska; Katarzyna Osiak; Krystyna Domanska-Janik; Bartłomiej H Noszczyk Journal: Neural Regen Res Date: 2021-05 Impact factor: 5.135