Literature DB >> 25362639

The sarcoplasmic reticulum and the evolution of the vertebrate heart.

Holly A Shiels1, Gina L J Galli2.   

Abstract

The sarcoplasmic reticulum (SR) is crucial for contraction and relaxation of the mammalian cardiomyocyte, but its role in other vertebrate classes is equivocal. Recent evidence suggests differences in SR function across species may have an underlying structural basis. Here, we discuss how SR recruitment relates to the structural organization of the cardiomyocyte to provide new insight into the evolution of cardiac design and function in vertebrates. ©2014 Int. Union Physiol. Sci./Am. Physiol. Soc.

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Year:  2014        PMID： 25362639     DOI： 10.1152/physiol.00015.2014

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


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