| Literature DB >> 25355676 |
Shota Yamazaki1, Koji Yamamoto, Makio Tokunaga, Kumiko Sakata-Sogawa, Masahiko Harata.
Abstract
RNA microarray analyses revealed that nuclear actin activated many human transcription factor genes including OCT4, which is required for gene reprogramming. Oct4 is known to be activated by nuclear actin in Xenopus oocytes. Our findings imply that this process of OCT4 activation is conserved in vertebrates and among cell types and could be used for gene reprogramming of human cells.Entities:
Keywords: OCT4; nuclear actin; transcription; transcription microarray
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Year: 2014 PMID： 25355676 DOI： 10.1080/09168451.2014.972332
Source DB: PubMed Journal: Biosci Biotechnol Biochem ISSN： 0916-8451 Impact factor: 2.043