| Literature DB >> 2535492 |
C P Soh1, A S Donald, J Feeney, W T Morgan, W M Watkins.
Abstract
The tetrasaccharides GalNAc beta 1-4[NeuAc alpha 2-3]Gal beta 1-4Glc and GalNAc beta 1-4[NeuAc alpha 2-3]Gal beta 1-4GlcNAc were synthesised by enzymic transfer of GalNAc from UDP-GalNAc to 3'-sialyllactose (NeuAc alpha 2-3 Gal beta 1-4Glc) and 3'-sialyl-N-acetyllactosamine (NeuAc alpha 2-3Gal beta 1-4GlcNAc). The structures of the products were established by methylation and 1H-500 MHz NMR spectroscopy. In Sda serological tests the product formed with 3'-sialyl-N-acetyllactosamine was highly active whereas that formed with 3'-sialyllactose had only weak activity.Entities:
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Year: 1989 PMID: 2535492 DOI: 10.1007/bf01047851
Source DB: PubMed Journal: Glycoconj J ISSN: 0282-0080 Impact factor: 2.916