Sudhir Singh Gangwar1, N Monisha2, Jainaf Nachiya2, Kanchana Narasingarao3, S Parimalakrishnan2, Seo Pratap Singh4. 1. Department of Pharmaceutical Sciences, GSVM Medical College, Kanpur, Uttar Pradesh, India. 2. Department of Pharmacy, Annamalai University, Annamalai Nagar, Tamil Nadu, India. 3. Andhra Yuvathi Mandali, School of Pharmacy, Barkatpura, Hyderabad, Andhra Pradesh. 4. Department of Pharmacology, GSVM Medical College, Kanpur, Uttar Pradesh, India.
Abstract
BACKGROUND: Drug related problem (DRPs) is a key factor which will affect the outcome of therapy and safety. OBJECTIVE: To assess the DRPs in type 2 diabetes mellitus (T2DM) patients and psychological aspects of patients by community pharmacists to observe the rate of DRP. METHODS: Prospective randomized controlled intervention study involved T2DM patients and conducted in two community pharmacies at Kanpur from January 2012 to December 2012. The assessment of DRPs was based on the PCNE. Changes in glycosylated hemoglobin (HBA1c), low density lipoproteins (LDL), blood pressure(BP), foot examinations, changes medical and medication utilization were studied. Using as control group, received usual care, and interventional group provided, intervened with use of the standard treatment guidelines (STG). Researcher provided the knowledge to community pharmacists and patients. Baseline and interventional data were collected at 0,3,6,9 and 12 months. RESULTS: Over the 12 month study, participants' average HBA1C reduced from 8.9% at initial visit to 7.5%. During this time, the eye examination rate was raised from 31% to 48%, and the foot examination rate was raised from 35% to 50%. CONCLUSION: The intervention of pharmacists showed little influence on any of the intermediate health outcomes in T2DM.
RCT Entities:
BACKGROUND: Drug related problem (DRPs) is a key factor which will affect the outcome of therapy and safety. OBJECTIVE: To assess the DRPs in type 2 diabetes mellitus (T2DM) patients and psychological aspects of patients by community pharmacists to observe the rate of DRP. METHODS: Prospective randomized controlled intervention study involved T2DM patients and conducted in two community pharmacies at Kanpur from January 2012 to December 2012. The assessment of DRPs was based on the PCNE. Changes in glycosylated hemoglobin (HBA1c), low density lipoproteins (LDL), blood pressure(BP), foot examinations, changes medical and medication utilization were studied. Using as control group, received usual care, and interventional group provided, intervened with use of the standard treatment guidelines (STG). Researcher provided the knowledge to community pharmacists and patients. Baseline and interventional data were collected at 0,3,6,9 and 12 months. RESULTS: Over the 12 month study, participants' average HBA1C reduced from 8.9% at initial visit to 7.5%. During this time, the eye examination rate was raised from 31% to 48%, and the foot examination rate was raised from 35% to 50%. CONCLUSION: The intervention of pharmacists showed little influence on any of the intermediate health outcomes in T2DM.
Entities:
Keywords:
Drug related problems; Medication review; PCNE classification; Psychological behavior; Type 2 Diabetes Mellitus
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