| Literature DB >> 25352143 |
Abstract
Fluorescence anisotropy can be utilized in drug discovery screening assays to identify compounds that disrupt medicinally important RNA-macromolecular complexes. Here we describe the application of this technique to monitor tRNA binding to T box riboswitch antiterminator RNA.Mesh:
Substances:
Year: 2015 PMID: 25352143 DOI: 10.1007/978-1-4939-1896-6_11
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745