Literature DB >> 25352143

Fluorescence anisotropy: analysis of tRNA binding to the T box riboswitch antiterminator RNA.

S Zhou1, R Anupam, J V Hines.   

Abstract

Fluorescence anisotropy can be utilized in drug discovery screening assays to identify compounds that disrupt medicinally important RNA-macromolecular complexes. Here we describe the application of this technique to monitor tRNA binding to T box riboswitch antiterminator RNA.

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Year:  2015        PMID: 25352143     DOI: 10.1007/978-1-4939-1896-6_11

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  2 in total

1.  Oxime ether lipids containing hydroxylated head groups are more superior siRNA delivery agents than their nonhydroxylated counterparts.

Authors:  Kshitij Gupta; Stephanie J Mattingly; Ralph J Knipp; Kirill A Afonin; Mathias Viard; Joseph T Bergman; Marissa Stepler; Michael H Nantz; Anu Puri; Bruce A Shapiro
Journal:  Nanomedicine (Lond)       Date:  2015-06-24       Impact factor: 5.307

2.  Factors that influence T box riboswitch efficacy and tRNA affinity.

Authors:  C Zeng; S Zhou; S C Bergmeier; J V Hines
Journal:  Bioorg Med Chem       Date:  2015-07-16       Impact factor: 3.641

  2 in total

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