Literature DB >> 25350183

Frequency and outcomes of submandibular gland obstruction following resection of squamous cell carcinomas in the vicinity of the submandibular duct.

D W H Wong1, A Kamisetty, D Lowe, S N Rogers.   

Abstract

INTRODUCTION: The aim of this study was to report rates, associated factors and outcomes of submandibular gland obstruction following surgery for squamous cell carcinoma in the anterior floor of the mouth (FOM) or ventral tongue without a neck dissection where resection has involved (or has been in very close proximity to) the submandibular duct.
METHODS: A retrospective case note review was carried out for the period January 2007 to December 2011. Only patients who received primary local surgical resection for squamous cell carcinoma of the anterior FOM or ventral tongue were included.
RESULTS: Fifty-two patients were analysed. Fifteen (29%) developed submandibular gland symptoms following surgery. Symptoms resolved spontaneously for 14 (93%) and 1 patient required the submandibular duct to be repositioned. Comparatively, 2 patients (13%) developed symptoms when the duct was repositioned during primary surgery. No patients had their submandibular gland removed.
CONCLUSIONS: Resection of small tumours associated with the FOM and ventral tongue in proximity to the submandibular duct is associated with obstructive symptoms in about a quarter of patients; this is reduced by half when redirecting the duct. Symptoms are self-limiting and self-resolving. A prospective clinical trial comparing duct repositioning with subcapsular gland excision would help clarify potential benefits and best treatment modalities.

Entities:  

Mesh:

Year:  2014        PMID: 25350183      PMCID: PMC4474102          DOI: 10.1308/003588414X14055925058436

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  6 in total

1.  Complications following interventional laser surgery for oral cancer and precancerous lesions.

Authors:  M L Goodson; K Sugden; S Kometa; P J Thomson
Journal:  Br J Oral Maxillofac Surg       Date:  2012-02-01       Impact factor: 1.651

2.  De-escalation of surgery for early oral cancer--is it oncologically safe?

Authors:  Conor P Barry; Chetan Katre; Elena Papa; James S Brown; Richard J Shaw; Fazilet Bekiroglu; Derek Lowe; Simon N Rogers
Journal:  Br J Oral Maxillofac Surg       Date:  2012-03-22       Impact factor: 1.651

3.  Transplantation of the submandibular duct associated with resection for carcinoma.

Authors:  C W Stimson; S G Leban
Journal:  Oral Surg Oral Med Oral Pathol       Date:  1983-08

4.  Fear of recurrence following head and neck cancer in the outpatient clinic.

Authors:  S N Rogers; B Scott; D Lowe; G Ozakinci; G M Humphris
Journal:  Eur Arch Otorhinolaryngol       Date:  2010-06-27       Impact factor: 2.503

5.  Submandibular duct repositioning after excision of floor of mouth cancer.

Authors:  R A Ord; V E Lee
Journal:  J Oral Maxillofac Surg       Date:  1996-09       Impact factor: 1.895

6.  Incidence of Wharton's duct stenosis in floor of the mouth cancers excised with scalpel or cautery vs CO2 laser.

Authors:  R Mihail; J T Zajtchuk; R K Davis
Journal:  Head Neck Surg       Date:  1987 Mar-Apr
  6 in total

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