Literature DB >> 25348541

Contaminated handwashing sinks as the source of a clonal outbreak of KPC-2-producing Klebsiella oxytoca on a hematology ward.

Eva Leitner1, Gernot Zarfel1, Josefa Luxner1, Kathrin Herzog2, Shiva Pekard-Amenitsch3, Martin Hoenigl4, Thomas Valentin4, Gebhard Feierl1, Andrea J Grisold1, Christoph Högenauer2, Heinz Sill5, Robert Krause4, Ines Zollner-Schwetz6.   

Abstract

We investigated sinks as possible sources of a prolonged Klebsiella pneumonia carbapenemase (KPC)-producing Klebsiella oxytoca outbreak. Seven carbapenem-resistant K. oxytoca isolates were identified in sink drains in 4 patient rooms and in the medication room. Investigations for resistance genes and genetic relatedness of patient and environmental isolates revealed that all the isolates harbored the blaKPC-2 and blaTEM-1 genes and were genetically indistinguishable. We describe here a clonal outbreak caused by KPC-2-producing K. oxytoca, and handwashing sinks were a possible reservoir.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

Entities:  

Mesh：

Substances：

Year:  2014        PMID： 25348541      PMCID： PMC4291428          DOI： 10.1128/AAC.04306-14

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting.

Authors:  Teresa C Horan; Mary Andrus; Margaret A Dudeck
Journal:  Am J Infect Control       Date:  2008-06       Impact factor: 2.918

2.  Outbreak of OXY-2-Producing Klebsiella oxytoca in a renal transplant unit.

Authors:  Mariela Soledad Zárate; Ana C Gales; Renata C Picão; Gervasio Soler Pujol; Alejandra Lanza; Jorgelina Smayevsky
Journal:  J Clin Microbiol       Date:  2008-04-16       Impact factor: 5.948

3.  Transmission of extended-spectrum β-lactamase Klebsiella oxytoca via the breathing circuit of a transport ventilator: root cause analysis and infection control recommendations.

Authors:  S Schulz-Stübner; E Kniehl
Journal:  Infect Control Hosp Epidemiol       Date:  2011-08       Impact factor: 3.254

4.  New genetic environments of aac(6')-Ib-cr gene in a multiresistant Klebsiella oxytoca strain causing an outbreak in a pediatric intensive care unit.

Authors:  Elena Ruiz; Antonio Rezusta; Yolanda Sáenz; Rosa Rocha-Gracia; Laura Vinué; Ana Vindel; Cruz Villuendas; Maria Luisa Azañedo; Maria Luisa Monforte; Maria José Revillo; Carmen Torres
Journal:  Diagn Microbiol Infect Dis       Date:  2011-02       Impact factor: 2.803

5.  Neonatal intensive care unit outbreak caused by a strain of Klebsiella oxytoca resistant to aztreonam due to overproduction of chromosomal beta-lactamase.

Authors:  S H Jeong; W M Kim; C L Chang; J M Kim; K Lee; Y Chong; H Y Hwang; Y W Baek; H K Chung; I G Woo; J Y Ku
Journal:  J Hosp Infect       Date:  2001-08       Impact factor: 3.926

6.  Nosocomial outbreak of Klebsiella pneumoniae carbapenemase-producing Klebsiella oxytoca in Austria.

Authors:  Martin Hoenigl; Thomas Valentin; Gernot Zarfel; Benjamin Wuerstl; Eva Leitner; Helmut J F Salzer; Josefa Posch; Robert Krause; Andrea J Grisold
Journal:  Antimicrob Agents Chemother       Date:  2012-01-30       Impact factor: 5.191

7.  A cluster of nosocomial Klebsiella oxytoca bloodstream infections in a university hospital.

Authors:  Yesim Cetinkaya Sardan; Pinar Zarakolu; Belgin Altun; Aycan Yildirim; Gonul Yildirim; Gulsen Hascelik; Omrum Uzun
Journal:  Infect Control Hosp Epidemiol       Date:  2004-10       Impact factor: 3.254

8.  Emergence of carbapenem-resistant Klebsiella species possessing the class A carbapenem-hydrolyzing KPC-2 and inhibitor-resistant TEM-30 beta-lactamases in New York City.

Authors:  Patricia A Bradford; Simona Bratu; Carl Urban; Melissa Visalli; Noriel Mariano; David Landman; James J Rahal; Steven Brooks; Sanda Cebular; John Quale
Journal:  Clin Infect Dis       Date:  2004-06-14       Impact factor: 9.079

9.  Genotypes of Klebsiella oxytoca isolates from patients with nosocomial pneumonia are distinct from those of isolates from patients with antibiotic-associated hemorrhagic colitis.

Authors:  Kathrin A T Herzog; Georg Schneditz; Eva Leitner; Gebhard Feierl; Karl Martin Hoffmann; Ines Zollner-Schwetz; Robert Krause; Gregor Gorkiewicz; Ellen L Zechner; Christoph Högenauer
Journal:  J Clin Microbiol       Date:  2014-03-05       Impact factor: 5.948

Review 10.  Global spread of Carbapenemase-producing Enterobacteriaceae.

Authors:  Patrice Nordmann; Thierry Naas; Laurent Poirel
Journal:  Emerg Infect Dis       Date:  2011-10       Impact factor: 6.883
View more
  33 in total

1.  Effect of Meropenem Concentration on the Detection of Low Numbers of Carbapenem-Resistant Enterobacteriaceae.

Authors:  Windy D Tanner; Robyn M Atkinson; Ramesh K Goel; Christina A Porucznik; Lowell Scott Benson; James A VanDerslice
Journal:  Antimicrob Agents Chemother       Date:  2015-11-09       Impact factor: 5.191

2.  Carbapenem-resistant Enterobacteriaceae dispersal from sinks is linked to drain position and drainage rates in a laboratory model system.

Authors:  P Aranega-Bou; R P George; N Q Verlander; S Paton; A Bennett; G Moore
Journal:  J Hosp Infect       Date:  2018-12-18       Impact factor: 3.926

3. 

Authors: 
Journal:  Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz       Date:  2020-04       Impact factor: 1.513

4.  Genomic Investigation Reveals Contaminated Detergent as the Source of an Extended-Spectrum-β-Lactamase-Producing Klebsiella michiganensis Outbreak in a Neonatal Unit.

Authors:  Paul Chapman; Brian M Forde; Leah W Roberts; Haakon Bergh; Debra Vesey; Amy V Jennison; Susan Moss; David L Paterson; Scott A Beatson; Patrick N A Harris
Journal:  J Clin Microbiol       Date:  2020-04-23       Impact factor: 5.948

Review 5.  The Epidemiology, Evolution, and Treatment of KPC-Producing Organisms.

Authors:  Ann Marie Porreca; Kaede V Sullivan; Jason C Gallagher
Journal:  Curr Infect Dis Rep       Date:  2018-05-05       Impact factor: 3.725

6.  A Systematic Review and Meta-analyses of the Clinical Epidemiology of Carbapenem-Resistant Enterobacteriaceae.

Authors:  Karlijn van Loon; Anne F Voor In 't Holt; Margreet C Vos
Journal:  Antimicrob Agents Chemother       Date:  2017-12-21       Impact factor: 5.191

Review 7.  Sink-Related Outbreaks and Mitigation Strategies in Healthcare Facilities.

Authors:  Leighanne O Parkes; Susy S Hota
Journal:  Curr Infect Dis Rep       Date:  2018-08-20       Impact factor: 3.725

8.  A Prolonged Outbreak of KPC-3-Producing Enterobacter cloacae and Klebsiella pneumoniae Driven by Multiple Mechanisms of Resistance Transmission at a Large Academic Burn Center.

Authors:  Hajime Kanamori; Christian M Parobek; Jonathan J Juliano; David van Duin; Bruce A Cairns; David J Weber; William A Rutala
Journal:  Antimicrob Agents Chemother       Date:  2017-01-24       Impact factor: 5.191

9.  A Large, Refractory Nosocomial Outbreak of Klebsiella pneumoniae Carbapenemase-Producing Escherichia coli Demonstrates Carbapenemase Gene Outbreaks Involving Sink Sites Require Novel Approaches to Infection Control.

Authors:  V Decraene; H T T Phan; R George; D H Wyllie; N Stoesser; J Cawthorne; O Akinremi; Z Aiken; P Cleary; A Dodgson; L Pankhurst; D W Crook; C Lenney; A S Walker; N Woodford; R Sebra; F Fath-Ordoubadi; A J Mathers; A C Seale; M Guiver; A McEwan; V Watts; W Welfare
Journal:  Antimicrob Agents Chemother       Date:  2018-11-26       Impact factor: 5.191

10.  Droplet- Rather than Aerosol-Mediated Dispersion Is the Primary Mechanism of Bacterial Transmission from Contaminated Hand-Washing Sink Traps.

Authors:  Shireen M Kotay; Rodney M Donlan; Christine Ganim; Katie Barry; Bryan E Christensen; Amy J Mathers
Journal:  Appl Environ Microbiol       Date:  2019-01-09       Impact factor: 4.792
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.