Literature DB >> 25347379

Multicystic dysplastic kidney: is an initial voiding cystourethrogram necessary?

Adam C Calaway1, Benjamin Whittam, Konrad M Szymanski, Rosalia Misseri, Martin Kaefer, Richard C Rink, Boaz Karymazn, Mark P Cain.   

Abstract

INTRODUCTION: Traditionally, a voiding cystourethrogram (VCUG) has been obtained in patients diagnosed with multicystic dysplastic kidney (MCDK) because of published vesicoureteral reflux (VUR) rates between 10%-20%. However, with the diagnosis and treatment of low grade VUR undergoing significant changes, we questioned the utility of obtaining a VCUG in healthy patients with a MCDK. We reviewed our experience to see how many of the patients with documented VUR required surgical intervention.
MATERIALS AND METHODS: We performed a retrospective review of children diagnosed with unilateral MCDK from 2002 to 2012 who also underwent a VCUG.
RESULTS: A total of 133 patients met our inclusion criteria. VUR was identified in 23 (17.3%) children. Four patients underwent ureteral reimplant (3.0%). Indications for surgical therapy included breakthrough urinary tract infections (2 patients), evidence of dysplasia/scarring (1 patient) and non-resolving reflux (1 patient). All patients with a history of VUR who are toilet trained, regardless of the grade or treatment, are currently being followed off antibiotic prophylaxis. To date, none have had a febrile urinary tract infection (UTI) since cessation of prophylactic antibiotics. Hydronephrosis in the contralateral kidney was not predictive of VUR (p = 0.99).
CONCLUSION: Routine VCUG in healthy children diagnosed with unilateral MCDK may not be warranted given the low incidence of clinically significant VUR. If a more conservative strategy is preferred, routine VCUG may be withheld in those children without normal kidney hydronephrosis and considered in patients with normal kidney hydronephrosis. If a VCUG is not performed the family should be instructed in signs and symptoms of urinary tract infection.

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Year:  2014        PMID: 25347379

Source DB:  PubMed          Journal:  Can J Urol        ISSN: 1195-9479            Impact factor:   1.344


  4 in total

1.  Multicystic dysplastic kidney (MCDK) in the neonate: The role of the urologist.

Authors:  Karen Psooy
Journal:  Can Urol Assoc J       Date:  2016 Jan-Feb       Impact factor: 1.862

Review 2.  Update on Multicystic Dysplastic Kidney.

Authors:  Diana Cardona-Grau; Barry A Kogan
Journal:  Curr Urol Rep       Date:  2015-10       Impact factor: 3.092

3.  Necessity of performing voiding cystourethrography for children with unilateral multicystic dysplastic kidney.

Authors:  Kazuna Yamamoto; Koichi Kamei; Mai Sato; Masao Ogura; Mari Suzuki; Yuichi Hasegawa; Katsuhiko Ueoka; Shuichi Ito; Kenji Ishikura
Journal:  Pediatr Nephrol       Date:  2018-09-25       Impact factor: 3.714

4.  Retrospective evaluation of the pediatric multicystic dysplastic kidney patients: experience of two centers from southeastern Turkey

Authors:  Mehtap Akbalık Kara; Aysel Taktak; Caner Alparslan
Journal:  Turk J Med Sci       Date:  2021-06-28       Impact factor: 0.973

  4 in total

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