Literature DB >> 25346642

Rational therapy from bench to bedside for a rare epilepsy.

Gustavo A Patino, Jack Parent.   

Abstract

Entities:  

Year:  2014        PMID： 25346642      PMCID： PMC4189645          DOI： 10.5698/1535-7597-14.5.286

Source DB:  PubMed          Journal:  Epilepsy Curr        ISSN： 1535-7511            Impact factor:   7.500


× No keyword cloud information.
  9 in total

Review 1.  Development of everolimus, a novel oral mTOR inhibitor, across a spectrum of diseases.

Authors:  David Lebwohl; Ozlem Anak; Tarek Sahmoud; Judith Klimovsky; Ingrid Elmroth; Tomas Haas; Joseph Posluszny; Stephen Saletan; William Berg
Journal:  Ann N Y Acad Sci       Date:  2013-05-09       Impact factor: 5.691

2.  STRADalpha deficiency results in aberrant mTORC1 signaling during corticogenesis in humans and mice.

Authors:  Ksenia A Orlova; Whitney E Parker; Gregory G Heuer; Victoria Tsai; Jason Yoon; Marianna Baybis; Robert S Fenning; Kevin Strauss; Peter B Crino
Journal:  J Clin Invest       Date:  2010-04-26       Impact factor: 14.808

Review 3.  mTOR: from growth signal integration to cancer, diabetes and ageing.

Authors:  Roberto Zoncu; Alejo Efeyan; David M Sabatini
Journal:  Nat Rev Mol Cell Biol       Date:  2010-12-15       Impact factor: 94.444

Review 4.  mTOR: A pathogenic signaling pathway in developmental brain malformations.

Authors:  Peter B Crino
Journal:  Trends Mol Med       Date:  2011-09-02       Impact factor: 11.951

Review 5.  Dissecting the role of mTOR: lessons from mTOR inhibitors.

Authors:  Ryan J O Dowling; Ivan Topisirovic; Bruno D Fonseca; Nahum Sonenberg
Journal:  Biochim Biophys Acta       Date:  2009-12-11

6.  Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex.

Authors:  Ling-Hui Zeng; Lin Xu; David H Gutmann; Michael Wong
Journal:  Ann Neurol       Date:  2008-04       Impact factor: 10.422

7.  Rapamycin prevents seizures after depletion of STRADA in a rare neurodevelopmental disorder.

Authors:  Whitney E Parker; Ksenia A Orlova; William H Parker; Jacqueline F Birnbaum; Vera P Krymskaya; Dmitry A Goncharov; Marianna Baybis; Jelte Helfferich; Kei Okochi; Kevin A Strauss; Peter B Crino
Journal:  Sci Transl Med       Date:  2013-04-24       Impact factor: 17.956

8.  Polyhydramnios, megalencephaly and symptomatic epilepsy caused by a homozygous 7-kilobase deletion in LYK5.

Authors:  Erik G Puffenberger; Kevin A Strauss; Keri E Ramsey; David W Craig; Dietrich A Stephan; Donna L Robinson; Christine L Hendrickson; Steven Gottlieb; David A Ramsay; Victoria M Siu; Gregory G Heuer; Peter B Crino; D Holmes Morton
Journal:  Brain       Date:  2007-05-23       Impact factor: 13.501

Review 9.  Everolimus in the treatment of subependymal giant cell astrocytomas, angiomyolipomas, and pulmonary and skin lesions associated with tuberous sclerosis complex.

Authors:  David Neal Franz
Journal:  Biologics       Date:  2013-10-10
  9 in total
  1 in total

Review 1.  Mechanistic target of rapamycin signaling in human nervous system development and disease.

Authors:  Marie Girodengo; Sila K Ultanir; Joseph M Bateman
Journal:  Front Mol Neurosci       Date:  2022-09-26       Impact factor: 6.261
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.