Literature DB >> 25343845

Biomarkers in acute kidney injury: are we ready for prime time?

Prasad Devarajan1, Patrick Murray.   

Abstract

Novel biomarkers are required to improve the timely detection of early acute kidney injury (AKI) and to improve the differential diagnosis, prognostic assessment, and management of AKI cases. It is anticipated that novel biomarkers of early structural AKI ('acute kidney damage') will provide critical diagnostic and prognostic stratification and complement functional markers such as serum creatinine. Further studies are required to conclusively demonstrate the association between early kidney damage biomarkers and clinical outcomes, both with and independently of functional markers, and to discern whether or not randomization to a treatment for AKI based on high structural/damage biomarker levels results in an improvement in kidney function and clinical outcomes. 2014 S. Karger AG, Basel.

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Year:  2014        PMID： 25343845      PMCID： PMC5002919          DOI： 10.1159/000363206

Source DB:  PubMed          Journal:  Nephron Clin Pract        ISSN： 1660-2110


  16 in total

1.  Diagnostic and prognostic stratification in the emergency department using urinary biomarkers of nephron damage: a multicenter prospective cohort study.

Authors:  Thomas L Nickolas; Kai M Schmidt-Ott; Pietro Canetta; Catherine Forster; Eugenia Singer; Meghan Sise; Antje Elger; Omar Maarouf; David Antonio Sola-Del Valle; Matthew O'Rourke; Evan Sherman; Peter Lee; Abdallah Geara; Philip Imus; Achuta Guddati; Allison Polland; Wasiq Rahman; Saban Elitok; Nasir Malik; James Giglio; Suzanne El-Sayegh; Prasad Devarajan; Sudarshan Hebbar; Subodh J Saggi; Barry Hahn; Ralph Kettritz; Friedrich C Luft; Jonathan Barasch
Journal:  J Am Coll Cardiol       Date:  2012-01-17       Impact factor: 24.094

2.  Urinary biomarkers of AKI and mortality 3 years after cardiac surgery.

Authors:  Steven G Coca; Amit X Garg; Heather Thiessen-Philbrook; Jay L Koyner; Uptal D Patel; Harlan M Krumholz; Michael G Shlipak; Chirag R Parikh
Journal:  J Am Soc Nephrol       Date:  2013-12-19       Impact factor: 10.121

3.  Plasma inflammatory and apoptosis markers are associated with dialysis dependence and death among critically ill patients receiving renal replacement therapy.

Authors:  Raghavan Murugan; Xiaoyan Wen; Nilesh Shah; Minjae Lee; Lan Kong; Francis Pike; Christopher Keener; Mark Unruh; Kevin Finkel; Anitha Vijayan; Paul M Palevsky; Emil Paganini; Melinda Carter; Michele Elder; John A Kellum
Journal:  Nephrol Dial Transplant       Date:  2014-03-11       Impact factor: 5.992

4.  Temporal relationship and predictive value of urinary acute kidney injury biomarkers after pediatric cardiopulmonary bypass.

Authors:  Catherine D Krawczeski; Stuart L Goldstein; Jessica G Woo; Yu Wang; Nuntawan Piyaphanee; Qing Ma; Michael Bennett; Prasad Devarajan
Journal:  J Am Coll Cardiol       Date:  2011-11-22       Impact factor: 24.094

5.  Fluid accumulation, recognition and staging of acute kidney injury in critically-ill patients.

Authors:  Etienne Macedo; Josée Bouchard; Sharon H Soroko; Glenn M Chertow; Jonathan Himmelfarb; T Alp Ikizler; Emil P Paganini; Ravindra L Mehta
Journal:  Crit Care       Date:  2010-05-06       Impact factor: 9.097

Review 6.  Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: a critical evaluation of current status.

Authors:  Anja Haase-Fielitz; Michael Haase; Prasad Devarajan
Journal:  Ann Clin Biochem       Date:  2014-02-11       Impact factor: 2.057

Review 7.  Acute kidney injury: an increasing global concern.

Authors:  Norbert H Lameire; Arvind Bagga; Dinna Cruz; Jan De Maeseneer; Zoltan Endre; John A Kellum; Kathleen D Liu; Ravindra L Mehta; Neesh Pannu; Wim Van Biesen; Raymond Vanholder
Journal:  Lancet       Date:  2013-05-31       Impact factor: 79.321

8.  Creatinine kinetics and the definition of acute kidney injury.

Authors:  Sushrut S Waikar; Joseph V Bonventre
Journal:  J Am Soc Nephrol       Date:  2009-02-25       Impact factor: 10.121

9.  Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury.

Authors:  Kianoush Kashani; Ali Al-Khafaji; Thomas Ardiles; Antonio Artigas; Sean M Bagshaw; Max Bell; Azra Bihorac; Robert Birkhahn; Cynthia M Cely; Lakhmir S Chawla; Danielle L Davison; Thorsten Feldkamp; Lui G Forni; Michelle Ng Gong; Kyle J Gunnerson; Michael Haase; James Hackett; Patrick M Honore; Eric A J Hoste; Olivier Joannes-Boyau; Michael Joannidis; Patrick Kim; Jay L Koyner; Daniel T Laskowitz; Matthew E Lissauer; Gernot Marx; Peter A McCullough; Scott Mullaney; Marlies Ostermann; Thomas Rimmelé; Nathan I Shapiro; Andrew D Shaw; Jing Shi; Amy M Sprague; Jean-Louis Vincent; Christophe Vinsonneau; Ludwig Wagner; Michael G Walker; R Gentry Wilkerson; Kai Zacharowski; John A Kellum
Journal:  Crit Care       Date:  2013-02-06       Impact factor: 9.097

10.  Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference.

Authors:  Patrick T Murray; Ravindra L Mehta; Andrew Shaw; Claudio Ronco; Zoltan Endre; John A Kellum; Lakhmir S Chawla; Dinna Cruz; Can Ince; Mark D Okusa
Journal:  Kidney Int       Date:  2013-10-09       Impact factor: 10.612
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  10 in total

Review 1.  Novel acute kidney injury biomarkers: their characteristics, utility and concerns.

Authors:  Braian M Beker; Mateo G Corleto; Cecilia Fieiras; Carlos G Musso
Journal:  Int Urol Nephrol       Date:  2018-01-06       Impact factor: 2.370

Review 2.  Biomarkers for Diagnosis and Prognosis of AKI in Children: One Size Does Not Fit All.

Authors:  Jason H Greenberg; Chirag R Parikh
Journal:  Clin J Am Soc Nephrol       Date:  2017-06-30       Impact factor: 8.237

3.  The urinary excretion of an organic anion transporter as an early biomarker of methotrexate-induced kidney injury.

Authors:  María J Severin; Mara S Trebucobich; Patricia Buszniez; Anabel Brandoni; Adriana M Torres
Journal:  Toxicol Res (Camb)       Date:  2016-01-07       Impact factor: 3.524

Review 4.  Bridging translation for acute kidney injury with better preclinical modeling of human disease.

Authors:  Nataliya I Skrypnyk; Leah J Siskind; Sarah Faubel; Mark P de Caestecker
Journal:  Am J Physiol Renal Physiol       Date:  2016-03-09

5.  Biomarkers and surrogate endpoints in kidney disease.

Authors:  Erum A Hartung
Journal:  Pediatr Nephrol       Date:  2015-05-16       Impact factor: 3.714

6.  A Pilot Study Identifying a Set of microRNAs As Precise Diagnostic Biomarkers of Acute Kidney Injury.

Authors:  Elia Aguado-Fraile; Edurne Ramos; Elisa Conde; Macarena Rodríguez; Laura Martín-Gómez; Aurora Lietor; Ángel Candela; Belen Ponte; Fernando Liaño; María Laura García-Bermejo
Journal:  PLoS One       Date:  2015-06-16       Impact factor: 3.240

Review 7.  Methodological issues in current practice may lead to bias in the development of biomarker combinations for predicting acute kidney injury.

Authors:  Allison Meisner; Kathleen F Kerr; Heather Thiessen-Philbrook; Steven G Coca; Chirag R Parikh
Journal:  Kidney Int       Date:  2016-02       Impact factor: 10.612

Review 8.  Volume-related weight gain as an independent indication for renal replacement therapy in the intensive care units.

Authors:  Tibor Fülöp; Lajos Zsom; Mihály B Tapolyai; Miklos Z Molnar; László Rosivall
Journal:  J Renal Inj Prev       Date:  2016-11-06

Review 9.  Biomarker-Guided Risk Assessment for Acute Kidney Injury: Time for Clinical Implementation?

Authors:  Christian Albert; Michael Haase; Annemarie Albert; Antonia Zapf; Rüdiger Christian Braun-Dullaeus; Anja Haase-Fielitz
Journal:  Ann Lab Med       Date:  2020-08-25       Impact factor: 3.464

10.  Validation of an enzyme-linked immunosorbent assay (ELISA) for quantification of endostatin levels in mice as a biomarker of developing glomerulonephritis.

Authors:  Jacqueline Wallwitz; Petra Aigner; Elisabeth Gadermaier; Eva Bauer; Emilio Casanova; Anton Bauer; Dagmar Stoiber
Journal:  PLoS One       Date:  2019-08-12       Impact factor: 3.240
  10 in total

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