Literature DB >> 25343387

Review finds that severe periodontitis affects 11% of the world population.

Derek Richards1.   

Abstract

DATA SOURCES: Medline, Embase and LILACS. Chief Dental Officers worldwide were contacted to request conference reports, theses, government reports and unpublished survey data. STUDY SELECTION: Selection was carried out independently by two reviewers. Longitudinal or crossover studies based on random samples representing national, subnational or community populations with SP defined as; a community periodontal index of treatment needs (CPITN) score of four, a clinical attachment loss (AL) more than 6 mm, or a gingival PD more than 5 mm. DATA EXTRACTION AND SYNTHESIS: Data extraction and synthesis followed Global Burden of Disease (GBD) 2010 standards and modeled using a Bayesian meta-regression tool developed for the GBD 2010. Countries were grouped in 21 regions and seven super-regions by geographical proximity and mean age of death.
RESULTS: Seventy two studies involving 291,170 patients were included. The majority of these (65) were prevalence studies. In 2010, SP was the sixth-most prevalent condition, affecting 10.8% (95% uncertainty interval [UI]: 10.1%-11.6%) or 743 million people worldwide. Between 1990 and 2010 the global age-standardised prevalence of SP in the entire population was static at 11.2% (95% UI: 10.4%-11.9% in 1990 and 10.5%-12.0% in 2010) a non-significant increase from the 1990 incidence of SP. The age-standardised incidence of SP in 2010 was 701 cases per 100,000 person-years (95% uncertainty interval: 599-823), a non-significant increase from the 1990 incidence of SP. Prevalence increased gradually with age, showing a steep increase between the third and fourth decades of life that was driven by a peak in incidence at around 38 years of age.
CONCLUSIONS: Policy makers need to be aware of a predictable increasing burden of SP due to the growing world population associated with an increasing life expectancy and a massive decrease in the prevalence of tooth loss throughout the world from 1990 to 2010. These changes underscore the enormous public health challenge posed by SP and are a microcosm of the epidemiologic transition to non-communicable diseases occurring in many countries.

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Year:  2014        PMID: 25343387     DOI: 10.1038/sj.ebd.6401037

Source DB:  PubMed          Journal:  Evid Based Dent        ISSN: 1462-0049


  1 in total

Review 1.  A systematic review of definitions of periodontitis and methods that have been used to identify this disease.

Authors:  Amir Savage; Kenneth A Eaton; David R Moles; Ian Needleman
Journal:  J Clin Periodontol       Date:  2009-06       Impact factor: 8.728

  1 in total
  12 in total

1.  An experimental murine model to study periodontitis.

Authors:  Julie Marchesan; Mustafa S Girnary; Li Jing; Michael Zhe Miao; Shaoping Zhang; Lu Sun; Thiago Morelli; Mark H Schoenfisch; Naohiro Inohara; Steven Offenbacher; Yizu Jiao
Journal:  Nat Protoc       Date:  2018-10       Impact factor: 13.491

2.  Toll-like receptor 4 gene polymorphism is associated with chronic periodontitis.

Authors:  Yuan-Sheng Ding; Yue Zhao; Yuan-Yuan Xiao; Gang Zhao
Journal:  Int J Clin Exp Med       Date:  2015-04-15

3.  Fusobacterium nucleatum infection of gingival epithelial cells leads to NLRP3 inflammasome-dependent secretion of IL-1β and the danger signals ASC and HMGB1.

Authors:  Fiona Q Bui; Larry Johnson; JoAnn Roberts; Shu-Chen Hung; Jungnam Lee; Kalina Rosenova Atanasova; Pei-Rong Huang; Özlem Yilmaz; David M Ojcius
Journal:  Cell Microbiol       Date:  2016-02-05       Impact factor: 3.715

4.  Application of deep machine learning for the radiographic diagnosis of periodontitis.

Authors:  Jennifer Chang; Ming-Feng Chang; Nikola Angelov; Chih-Yu Hsu; Hsiu-Wan Meng; Sally Sheng; Aaron Glick; Kearny Chang; Yun-Ru He; Yi-Bing Lin; Bing-Yan Wang; Srinivas Ayilavarapu
Journal:  Clin Oral Investig       Date:  2022-07-26       Impact factor: 3.606

Review 5.  Current Concepts in the Management of Periodontitis.

Authors:  TaeHyun Kwon; Ira B Lamster; Liran Levin
Journal:  Int Dent J       Date:  2021-02-19       Impact factor: 2.607

6.  Salivary Matrix Metalloproteinase-8 and -9 and Myeloperoxidase in Relation to Coronary Heart and Periodontal Diseases: A Subgroup Report from the PAROKRANK Study (Periodontitis and Its Relation to Coronary Artery Disease).

Authors:  Nilminie Rathnayake; Anders Gustafsson; Anna Norhammar; Barbro Kjellström; Björn Klinge; Lars Rydén; Taina Tervahartiala; Timo Sorsa
Journal:  PLoS One       Date:  2015-07-01       Impact factor: 3.240

7.  Simvastatin modulates gingival cytokine and MMP production in a rat model of ligature-induced periodontitis.

Authors:  José Carlos Elias Mouchrek Júnior; Cristina Gomes Macedo; Henrique Ballassini Abdalla; Ana Karina Saba; Lucas Novaes Teixeira; Adriana Quinzeiro E Silva Mouchrek; Marcelo Henrique Napimoga; Juliana Trindade Clemente-Napimoga; Alvaro Henrique Borges; Mateus Rodrigues Tonetto; Shelon Cristina Souza Pinto; Matheus Coelho Bandeca; Elizabeth Ferreira Martinez
Journal:  Clin Cosmet Investig Dent       Date:  2017-05-15

Review 8.  Oxidative Stress and Antioxidant System in Periodontitis.

Authors:  Yue Wang; Oleh Andrukhov; Xiaohui Rausch-Fan
Journal:  Front Physiol       Date:  2017-11-13       Impact factor: 4.566

Review 9.  An Evidence-Based Update on the Molecular Mechanisms Underlying Periodontal Diseases.

Authors:  Syed Saad B Qasim; Dalal Al-Otaibi; Reham Al-Jasser; Sarhang S Gul; Muhammad Sohail Zafar
Journal:  Int J Mol Sci       Date:  2020-05-28       Impact factor: 5.923

10.  DNA Laddering to Evaluate Cytogenetic Damage in Patients with Periodontitis.

Authors:  Baddam Harshitha; Bopparaju Subhada; Mohammed Mustafa; Hemlata Solanki; Nabeel Althaf Mammootty Safiya; Rahul Vinay Chandra Tiwari
Journal:  J Int Soc Prev Community Dent       Date:  2019-09-30
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