Wuxiang Xie1, Gang Li2, Dong Zhao1, Xueqin Xie3, Zaihua Wei2, Wei Wang1, Miao Wang1, Guoxing Li4, Wanru Liu3, Jiayi Sun1, Zhangrong Jia1, Qian Zhang1, Jing Liu1. 1. Department of Epidemiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing, China. 2. Information Statistics Center, Beijing Center for Diseases Prevention and Control, Beijing, China. 3. Beijing Public Health Information Center, Beijing, China. 4. Department of Occupational and Environmental Health, School of Public Health, Peking University, Beijing, China.
Abstract
OBJECTIVE: To assess the relationship between fine particulate matter (PM2.5) concentration and ischaemic heart disease (IHD) morbidity and mortality. METHODS: A time-series study conducted in Beijing from 1 January 2010 to 31 December 2012. Data on 369,469 IHD cases and 53,247 IHD deaths were collected by the Beijing Monitoring System for Cardiovascular Diseases, which covers all hospital admissions and deaths from IHD from Beijing's population of 19.61 million. RESULTS: The mean daily PM2.5 concentration was 96.2 μg/m(3) with a range from 3.9 to 493.9 μg/m(3). Only 15.3% of the daily PM2.5 concentrations achieved WHO Air Quality Guidelines target (25 μg/m(3)) in the study period. The dose-response relationships between PM2.5 and IHD morbidity and mortality were non-linear, with a steeper dose-response function at lower concentrations and a shallower response at higher concentrations. A 10 μg/m(3) increase in PM2.5 was associated with a 0.27% (95% CI 0.21 to 0.33%, p<2.00×10(-16)) increase in IHD morbidity and a 0.25% (95% CI 0.10 to 0.40%, p=1.15×10(-3)) increase in mortality on the same day. During the 3 years, there were 7703 cases and 1475 deaths advanced by PM2.5 pollution over expected rates if daily levels had not exceeded the WHO target. CONCLUSIONS: PM2.5 concentration was significantly associated with IHD morbidity and mortality in Beijing. Our findings provide a rationale for the urgent need for stringent control of air pollution to reduce PM2.5 concentration. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
OBJECTIVE: To assess the relationship between fine particulate matter (PM2.5) concentration and ischaemic heart disease (IHD) morbidity and mortality. METHODS: A time-series study conducted in Beijing from 1 January 2010 to 31 December 2012. Data on 369,469 IHD cases and 53,247 IHD deaths were collected by the Beijing Monitoring System for Cardiovascular Diseases, which covers all hospital admissions and deaths from IHD from Beijing's population of 19.61 million. RESULTS: The mean daily PM2.5 concentration was 96.2 μg/m(3) with a range from 3.9 to 493.9 μg/m(3). Only 15.3% of the daily PM2.5 concentrations achieved WHO Air Quality Guidelines target (25 μg/m(3)) in the study period. The dose-response relationships between PM2.5 and IHD morbidity and mortality were non-linear, with a steeper dose-response function at lower concentrations and a shallower response at higher concentrations. A 10 μg/m(3) increase in PM2.5 was associated with a 0.27% (95% CI 0.21 to 0.33%, p<2.00×10(-16)) increase in IHD morbidity and a 0.25% (95% CI 0.10 to 0.40%, p=1.15×10(-3)) increase in mortality on the same day. During the 3 years, there were 7703 cases and 1475 deaths advanced by PM2.5 pollution over expected rates if daily levels had not exceeded the WHO target. CONCLUSIONS: PM2.5 concentration was significantly associated with IHD morbidity and mortality in Beijing. Our findings provide a rationale for the urgent need for stringent control of air pollution to reduce PM2.5 concentration. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
Authors: Yao Wu; Man Li; Yaohua Tian; Yaying Cao; Jing Song; Zhe Huang; Xiaowen Wang; Yonghua Hu Journal: Environ Sci Pollut Res Int Date: 2019-03-11 Impact factor: 4.223
Authors: Yaghoub Hajizadeh; Negar Jafari; Farzad Fanaei; Reza Ghanbari; Amir Mohammadi; Ali Behnami; Azin Jafari; Mohammad Aghababayi; Ali Abdolahnejad Journal: J Environ Health Sci Eng Date: 2021-03-18