Literature DB >> 25340806

Role and regulation of RUNX2 in osteogenesis.

M Bruderer1, R G Richards, M Alini, M J Stoddart.   

Abstract

Runt-related transcription factor 2 (RUNX2) is a transcription factor closely associated with the osteoblast phenotype. While frequently referred to, the complexity of its regulation and its interactions within the osteoblast differentiation pathway are often overlooked. This review aims to summarise the knowledge of its regulation at the transcriptional, translational and post-translational level. In addition, the regulation of RUNX2 by factors commonly used during osteogenic studies will be discussed.

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Year:  2014        PMID： 25340806     DOI： 10.22203/ecm.v028a19

Source DB:  PubMed          Journal:  Eur Cell Mater        ISSN： 1473-2262            Impact factor:   3.942


  128 in total

1.  Panax notoginseng stimulates alkaline phosphatase activity, collagen synthesis, and mineralization in osteoblastic MC3T3-E1 cells.

Authors:  Zhe Ji; Yizhao Cheng; Puwei Yuan; Xiaoqian Dang; Xiong Guo; Weizhuo Wang
Journal:  In Vitro Cell Dev Biol Anim       Date:  2015-04-23       Impact factor: 2.416

2.  Aloin promotes osteogenesis of bone-marrow-derived mesenchymal stem cells via the ERK1/2-dependent Runx2 signaling pathway.

Authors:  Peng Li; Junchao Kong; Zhuming Chen; Shuai Huang; Guihe Lv; Bo Wei; Jinsong Wei; Kaipeng Jing; Juanhua Quan; Jiaqi Chu
Journal:  J Nat Med       Date:  2018-09-14       Impact factor: 2.343

3.  Cystathionine γ-Lyase-Hydrogen Sulfide Induces Runt-Related Transcription Factor 2 Sulfhydration, Thereby Increasing Osteoblast Activity to Promote Bone Fracture Healing.

Authors:  Yang Zheng; Feng Liao; Xianjuan Lin; Fengjiao Zheng; Jinghui Fan; Qinghua Cui; Jichun Yang; Bin Geng; Jun Cai
Journal:  Antioxid Redox Signal       Date:  2017-03-10       Impact factor: 8.401

4.  Differential bone remodeling mechanism in hindlimb unloaded rats and hibernating Daurian ground squirrels: a comparison between artificial and natural disuse.

Authors:  Xuli Gao; Siqi Wang; Jie Zhang; Shuyao Wang; Feiyan Bai; Jing Liang; Jiawei Wu; Huiping Wang; Yunfang Gao; Hui Chang
Journal:  J Comp Physiol B       Date:  2021-05-18       Impact factor: 2.200

5.  FGF Signaling Prevents the Terminal Differentiation of Odontoblasts.

Authors:  K Sagomonyants; I Kalajzic; P Maye; M Mina
Journal:  J Dent Res       Date:  2017-02-07       Impact factor: 6.116

6.  Chondrocyte-Specific RUNX2 Overexpression Accelerates Post-traumatic Osteoarthritis Progression in Adult Mice.

Authors:  Sarah E Catheline; Donna Hoak; Martin Chang; John P Ketz; Matthew J Hilton; Michael J Zuscik; Jennifer H Jonason
Journal:  J Bone Miner Res       Date:  2019-06-12       Impact factor: 6.741

7.  Differential analysis of genome-wide methylation and gene expression in mesenchymal stem cells of patients with fractures and osteoarthritis.

Authors:  Alvaro Del Real; Flor M Pérez-Campo; Agustín F Fernández; Carolina Sañudo; Carmen G Ibarbia; María I Pérez-Núñez; Wim Van Criekinge; Maarten Braspenning; María A Alonso; Mario F Fraga; Jose A Riancho
Journal:  Epigenetics       Date:  2016-12-16       Impact factor: 4.528

8.  [Construction of human telomerase reverse transcriptase periodontal ligament cell line mediated by adenovirus].

Authors:  Gui-Jun Sun; Xiao-Dong Qin; Shi-Qin Wang; Hui-Zhen Hu; Xiao-Yan Lu; Jia-Jia Jin; Sheng-Rong Wu; Xiang-Yi He
Journal:  Hua Xi Kou Qiang Yi Xue Za Zhi       Date:  2019-02-01

9.  Comparison of Periodontal Ligament Cell Lines with Adenovirus- and Lentivirus-Mediated Human Telomerase Reverse Transcription Expression.

Authors:  Guijun Sun; Yang Yang; Xiaoyan Lu; Qing Liu; Shengrong Wu; Jiajia Jin; Zixiao Huang; Xiangyi He
Journal:  Hum Gene Ther Methods       Date:  2019-02-28       Impact factor: 2.396

10.  Effects of substrate stiffness and cell-cell contact on mesenchymal stem cell differentiation.

Authors:  Angelo S Mao; Jae-Won Shin; David J Mooney
Journal:  Biomaterials       Date:  2016-05-05       Impact factor: 12.479
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